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    NPORT-P
    false
    
      
      
        
          0001572661
          XXXXXXXX
        
      
      
      
      
        S000054611
        C000171494
      
      
      
    
  
  
    
      Principal Exchange-Traded Funds
      811-23029
      0001572661
      549300AG76V5U32HWF10
      801 Grand Avenue
      DES MOINES
      
      50309
      515-235-1719
      Principal Healthcare Innovators ETF
      S000054611
      549300HI5VZD2P4JPY17
      2022-06-30
      2022-06-30
      N
    
    
      54390376.95
      1115490.71
      53274886.24
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      0.00000000
      
        
        
        
        
        
        
        
        
        
      
      N
      
        
          
        
        
        
        
      
      
      
      
      
    
    
      
        Cano Health Inc
        N/A
        Cano Health, Inc.
        13781Y103
        
          
        
        22452.00000000
        NS
        USD
        98339.76000000
        0.184589338317
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Ionis Pharmaceuticals Inc
        549300SI4ZGLG0BLUZ92
        Ionis Pharmaceuticals, Inc.
        462222100
        
          
        
        16140.00000000
        NS
        USD
        597502.80000000
        1.121546834109
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        MiMedx Group Inc
        N/A
        MiMedx Group, Inc.
        602496101
        
          
        
        12607.00000000
        NS
        USD
        43746.29000000
        0.082114281395
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Generation Bio Co
        N/A
        Generation Bio Co.
        37148K100
        
          
        
        6395.00000000
        NS
        USD
        41951.20000000
        0.078744795082
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        DermTech Inc
        N/A
        DermTech, Inc.
        24984K105
        
          
        
        3349.00000000
        NS
        USD
        18553.46000000
        0.034825902614
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ModivCare Inc
        549300EFZIFW7F7I0Q28
        ModivCare, Inc.
        60783X104
        
          
        
        2182.00000000
        NS
        USD
        184379.00000000
        0.346089899036
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Clovis Oncology Inc
        529900WCUY9ZAHMRV489
        Clovis Oncology, Inc.
        189464100
        
          
        
        15961.00000000
        NS
        USD
        28729.80000000
        0.053927473201
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        10X Genomics Inc
        5493003Z6741WNLG7H43
        10X Genomics, Inc.
        88025U109
        
          
        
        10638.00000000
        NS
        USD
        481369.50000000
        0.903558006358
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Absci Corp
        N/A
        Absci Corp.
        00091E109
        
          
        
        10389.00000000
        NS
        USD
        34491.48000000
        0.064742475177
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        2seventy bio Inc
        N/A
        2seventy bio, Inc.
        901384107
        
          
        
        4220.00000000
        NS
        USD
        55704.00000000
        0.104559585071
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Arrowhead Pharmaceuticals Inc
        549300O3CSB8T7OZ3D66
        Arrowhead Pharmaceuticals, Inc.
        04280A100
        
          
        
        12024.00000000
        NS
        USD
        423365.04000000
        0.794680326660
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Curis Inc
        5299000YO6CX4WMFVX06
        Curis, Inc.
        231269200
        
          
        
        10282.00000000
        NS
        USD
        10122.63000000
        0.019000753853
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Protagonist Therapeutics Inc
        N/A
        Protagonist Therapeutics, Inc.
        74366E102
        
          
        
        5432.00000000
        NS
        USD
        42967.12000000
        0.080651734865
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Rhythm Pharmaceuticals Inc
        529900JPNWXQ8DPLA551
        Rhythm Pharmaceuticals, Inc.
        76243J105
        
          
        
        5639.00000000
        NS
        USD
        23401.85000000
        0.043926607172
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Evolent Health Inc
        549300CZOCFHQ2BBTR11
        Evolent Health, Inc.
        30050B101
        
          
        
        10191.00000000
        NS
        USD
        312965.61000000
        0.587454299930
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Revance Therapeutics Inc
        549300N33TFDZHS81H11
        Revance Therapeutics, Inc.
        761330109
        
          
        
        8016.00000000
        NS
        USD
        110781.12000000
        0.207942480629
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Alnylam Pharmaceuticals Inc
        529900S3ZI14OWRJII50
        Alnylam Pharmaceuticals, Inc.
        02043Q107
        
          
        
        12147.00000000
        NS
        USD
        1771639.95000000
        3.325469231447
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Kezar Life Sciences Inc
        549300EV1V8GXBV18004
        Kezar Life Sciences, Inc.
        49372L100
        
          
        
        5513.00000000
        NS
        USD
        45592.51000000
        0.085579741634
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Anavex Life Sciences Corp
        549300K1I5L8COCQ8W36
        Anavex Life Sciences Corp.
        032797300
        
          
        
        8546.00000000
        NS
        USD
        85545.46000000
        0.160573707496
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Akebia Therapeutics Inc
        549300CBQEHMKEEGNX42
        Akebia Therapeutics, Inc.
        00972D105
        
          
        
        19631.00000000
        NS
        USD
        6931.71000000
        0.013011215019
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Viatris Inc
        254900ZZTSW7NL773X71
        Viatris, Inc.
        92556V106
        
          
        
        137406.00000000
        NS
        USD
        1438640.82000000
        2.700410871867
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Relay Therapeutics Inc
        N/A
        Relay Therapeutics, Inc.
        75943R102
        
          
        
        12149.00000000
        NS
        USD
        203495.75000000
        0.381973129108
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Kura Oncology Inc
        5493005QORQTZCZYOP39
        Kura Oncology, Inc.
        50127T109
        
          
        
        7473.00000000
        NS
        USD
        136980.09000000
        0.257119441574
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        SI-BONE Inc
        549300J8JGYVJJHV9C31
        SI-BONE, Inc.
        825704109
        
          
        
        3796.00000000
        NS
        USD
        50107.20000000
        0.094054072258
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        BioCryst Pharmaceuticals Inc
        549300Z0INP1Z5NP6J59
        BioCryst Pharmaceuticals, Inc.
        09058V103
        
          
        
        20720.00000000
        NS
        USD
        219217.60000000
        0.411483938252
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inogen Inc
        549300J8WJIVTOJ8IH97
        Inogen, Inc.
        45780L104
        
          
        
        2550.00000000
        NS
        USD
        61659.00000000
        0.115737459714
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Exact Sciences Corp
        549300VM3X1FYD4N9Z14
        Exact Sciences Corp.
        30063P105
        
          
        
        19791.00000000
        NS
        USD
        779567.49000000
        1.463292641279
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Intercept Pharmaceuticals Inc
        254900JMB8TX5P688V24
        Intercept Pharmaceuticals, Inc.
        45845P108
        
          
        
        3317.00000000
        NS
        USD
        45807.77000000
        0.085983796931
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Caribou Biosciences Inc
        N/A
        Caribou Biosciences, Inc.
        142038108
        
          
        
        6752.00000000
        NS
        USD
        36663.36000000
        0.068819217810
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Verve Therapeutics Inc
        N/A
        Verve Therapeutics, Inc.
        92539P101
        
          
        
        5404.00000000
        NS
        USD
        82573.12000000
        0.154994455789
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Keros Therapeutics Inc
        N/A
        Keros Therapeutics, Inc.
        492327101
        
          
        
        2627.00000000
        NS
        USD
        72584.01000000
        0.136244326591
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Omeros Corp
        549300CJWLXX2MXVVV71
        Omeros Corp.
        682143102
        
          
        
        7017.00000000
        NS
        USD
        19296.75000000
        0.036221100338
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Biora Therapeutics Inc
        5493005XOS7E58D57T10
        Biora Therapeutics, Inc.
        74319F107
        
          
        
        18600.00000000
        NS
        USD
        13020.00000000
        0.024439282594
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        PetIQ Inc
        549300GROACFGKVYOX14
        PetIQ, Inc.
        71639T106
        
          
        
        3268.00000000
        NS
        USD
        54869.72000000
        0.102993593928
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        BioLife Solutions Inc
        549300G2IVCMC2TJDW72
        BioLife Solutions, Inc.
        09062W204
        
          
        
        4672.00000000
        NS
        USD
        64520.32000000
        0.121108320549
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ATI Physical Therapy Inc
        N/A
        ATI Physical Therapy, Inc.
        00216W109
        
          
        
        22149.00000000
        NS
        USD
        31230.09000000
        0.058620660134
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Rubius Therapeutics Inc
        549300ER84PB0QV6HZ76
        Rubius Therapeutics, Inc.
        78116T103
        
          
        
        10107.00000000
        NS
        USD
        8598.02000000
        0.016138973927
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        23andMe Holding Co
        N/A
        23andMe Holding Co.
        90138Q108
        
          
        
        23694.00000000
        NS
        USD
        58761.12000000
        0.110297973674
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        G1 Therapeutics Inc
        529900TC35UPZQYRKW13
        G1 Therapeutics, Inc.
        3621LQ109
        
          
        
        4790.00000000
        NS
        USD
        23662.60000000
        0.044416049793
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cutera Inc
        529900NPKPEWJWR21Z42
        Cutera, Inc.
        232109108
        
          
        
        2027.00000000
        NS
        USD
        76012.50000000
        0.142679797864
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Brookdale Senior Living Inc
        LH7MQB13NWY7CJ9VC445
        Brookdale Senior Living, Inc.
        112463104
        
          
        
        20823.00000000
        NS
        USD
        94536.42000000
        0.177450252214
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sharecare Inc
        N/A
        Sharecare, Inc.
        81948W104
        
          
        
        38042.00000000
        NS
        USD
        60106.36000000
        0.112823065879
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Ocugen Inc
        549300JVNUI9CXWJLR09
        Ocugen, Inc.
        67577C105
        
          
        
        22383.00000000
        NS
        USD
        50809.41000000
        0.095372160479
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Prometheus Biosciences Inc
        N/A
        Prometheus Biosciences, Inc.
        74349U108
        
          
        
        4368.00000000
        NS
        USD
        123308.64000000
        0.231457350175
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Warby Parker Inc
        N/A
        Warby Parker, Inc.
        93403J106
        
          
        
        10690.00000000
        NS
        USD
        120369.40000000
        0.225940229056
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        agilon health Inc
        N/A
        agilon health, Inc.
        00857U107
        
          
        
        45642.00000000
        NS
        USD
        996364.86000000
        1.870233669784
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        AtriCure Inc
        N/A
        AtriCure, Inc.
        04963C209
        
          
        
        5165.00000000
        NS
        USD
        211041.90000000
        0.396137683052
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Myriad Genetics Inc
        52990044IHUOUMETT163
        Myriad Genetics, Inc.
        62855J104
        
          
        
        8979.00000000
        NS
        USD
        163148.43000000
        0.306238908263
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ChemoCentryx Inc
        529900YTTXUSFQTAKY40
        ChemoCentryx, Inc.
        16383L106
        
          
        
        7858.00000000
        NS
        USD
        194721.24000000
        0.365502873385
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Aclaris Therapeutics Inc
        5493000B2LQ9QTW1DF52
        Aclaris Therapeutics, Inc.
        00461U105
        
          
        
        6875.00000000
        NS
        USD
        95975.00000000
        0.180150548924
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Humanigen Inc
        549300ILAUCQNMJQXL47
        Humanigen, Inc.
        444863203
        
          
        
        7329.00000000
        NS
        USD
        12972.33000000
        0.024349803285
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Multiplan Corp
        N/A
        Multiplan Corp.
        62548M100
        
          
        
        71656.00000000
        NS
        USD
        393391.44000000
        0.738418169919
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Nektar Therapeutics
        5299005I24806IOIYE03
        Nektar Therapeutics
        640268108
        
          
        
        20707.00000000
        NS
        USD
        78686.60000000
        0.147699236081
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Lyell Immunopharma Inc
        N/A
        Lyell Immunopharma, Inc.
        55083R104
        
          
        
        26982.00000000
        NS
        USD
        175922.64000000
        0.330216829009
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        PMV Pharmaceuticals Inc
        N/A
        PMV Pharmaceuticals, Inc.
        69353Y103
        
          
        
        5091.00000000
        NS
        USD
        72546.75000000
        0.136174387446
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Pacific Biosciences of California Inc
        529900F1BWRE1M0KZN89
        Pacific Biosciences of California, Inc.
        69404D108
        
          
        
        24819.00000000
        NS
        USD
        109699.98000000
        0.205913119186
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Theravance Biopharma Inc
        5493007VTSXP4Z6MIW52
        Theravance Biopharma, Inc.
        000000000
        
          
        
        8381.00000000
        NS
        USD
        75931.86000000
        0.142528431985
        Long
        EC
        CORP
        KY
        
        N
        
        1
        
          N
          N
          N
        
      
      
        OraSure Technologies Inc
        529900GNNJPNM4XHXQ77
        OraSure Technologies, Inc.
        68554V108
        
          
        
        8112.00000000
        NS
        USD
        21983.52000000
        0.041264320867
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Teladoc Health Inc
        549300I2PVFBC9MFAC61
        Teladoc Health, Inc.
        87918A105
        
          
        
        18260.00000000
        NS
        USD
        606414.60000000
        1.138274790992
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sema4 Holdings Corp
        N/A
        Sema4 Holdings Corp.
        81663L101
        
          
        
        27487.00000000
        NS
        USD
        34633.62000000
        0.065009280064
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        BioMarin Pharmaceutical Inc
        NSLL8ITTRR0J5HEMR848
        BioMarin Pharmaceutical, Inc.
        09061G101
        
          
        
        20899.00000000
        NS
        USD
        1731900.13000000
        3.250875322751
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        908 Devices Inc
        N/A
        908 Devices, Inc.
        65443P102
        
          
        
        3505.00000000
        NS
        USD
        72167.95000000
        0.135463358241
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Berkeley Lights Inc
        549300LTLRE4N65CD358
        Berkeley Lights, Inc.
        084310101
        
          
        
        7590.00000000
        NS
        USD
        37722.30000000
        0.070806908587
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Eagle Pharmaceuticals Inc/DE
        549300TN20OLYTJVP152
        Eagle Pharmaceuticals, Inc.
        269796108
        
          
        
        1449.00000000
        NS
        USD
        64379.07000000
        0.120843186243
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Axonics Inc
        549300LJY4X7N57VJL05
        Axonics, Inc.
        05465P101
        
          
        
        5270.00000000
        NS
        USD
        298650.90000000
        0.560584772822
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sage Therapeutics Inc
        5493000JX4BJS9W6CN35
        Sage Therapeutics, Inc.
        78667J108
        
          
        
        6625.00000000
        NS
        USD
        213987.50000000
        0.401666742254
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Alignment Healthcare Inc
        N/A
        Alignment Healthcare, Inc.
        01625V104
        
          
        
        20990.00000000
        NS
        USD
        239495.90000000
        0.449547463923
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        CytomX Therapeutics Inc
        5493004VW2FW0QLL3345
        CytomX Therapeutics, Inc.
        23284F105
        
          
        
        7321.00000000
        NS
        USD
        13397.43000000
        0.025147740231
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        iRhythm Technologies Inc
        549300FJI72RJGDQS384
        iRhythm Technologies, Inc.
        450056106
        
          
        
        3369.00000000
        NS
        USD
        363953.07000000
        0.683160670414
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        LifeStance Health Group Inc
        N/A
        LifeStance Health Group, Inc.
        53228F101
        
          
        
        41997.00000000
        NS
        USD
        233503.32000000
        0.438299049477
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Definitive Healthcare Corp
        N/A
        Definitive Healthcare Corp.
        24477E103
        
          
        
        10927.00000000
        NS
        USD
        250556.11000000
        0.470308108911
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Beam Therapeutics Inc
        N/A
        Beam Therapeutics, Inc.
        07373V105
        
          
        
        7712.00000000
        NS
        USD
        298531.52000000
        0.560360689753
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Seres Therapeutics Inc
        549300GMXBE5NUWISF13
        Seres Therapeutics, Inc.
        81750R102
        
          
        
        10305.00000000
        NS
        USD
        35346.15000000
        0.066346739513
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Adaptive Biotechnologies Corp
        549300ZTF7OT1FW66Q96
        Adaptive Biotechnologies Corp.
        00650F109
        
          
        
        15886.00000000
        NS
        USD
        128517.74000000
        0.241235127975
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        GoodRx Holdings Inc
        N/A
        GoodRx Holdings, Inc.
        38246G108
        
          
        
        9055.00000000
        NS
        USD
        53605.60000000
        0.100620768589
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Travere Therapeutics Inc
        N/A
        Travere Therapeutics, Inc.
        89422G107
        
          
        
        7092.00000000
        NS
        USD
        171839.16000000
        0.322551904148
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cardiovascular Systems Inc
        549300NUBWKJMNMQ3287
        Cardiovascular Systems, Inc.
        141619106
        
          
        
        4552.00000000
        NS
        USD
        65366.72000000
        0.122697061623
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Senseonics Holdings Inc
        549300RCH6Z07TBHJ258
        Senseonics Holdings, Inc.
        81727U105
        
          
        
        51970.00000000
        NS
        USD
        53529.10000000
        0.100477173726
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Erasca Inc
        N/A
        Erasca, Inc.
        29479A108
        
          
        
        13605.00000000
        NS
        USD
        75779.85000000
        0.142243100545
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Collegium Pharmaceutical Inc
        54930049FXZMTLW8D496
        Collegium Pharmaceutical, Inc.
        19459J104
        
          
        
        3744.00000000
        NS
        USD
        66343.68000000
        0.124530871264
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Y-mAbs Therapeutics Inc
        N/A
        Y-mAbs Therapeutics, Inc.
        984241109
        
          
        
        4897.00000000
        NS
        USD
        74091.61000000
        0.139074177777
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        AnaptysBio Inc
        529900HH4WQT03IG1A12
        AnaptysBio, Inc.
        032724106
        
          
        
        3101.00000000
        NS
        USD
        62950.30000000
        0.118161303463
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Seagen Inc
        N/A
        Seagen, Inc.
        81181C104
        
          
        
        13767.00000000
        NS
        USD
        2435932.98000000
        4.572385136640
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Novocure Ltd
        213800YPP55UMHWA4826
        Novocure Ltd.
        000000000
        
          
        
        11876.00000000
        NS
        USD
        825382.00000000
        1.549289089575
        Long
        EC
        CORP
        JE
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Invitae Corp
        549300MYI59DZW1WIX92
        Invitae Corp.
        46185L103
        
          
        
        25623.00000000
        NS
        USD
        62520.12000000
        0.117353831068
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Alector Inc
        549300Z8RQOIY1JMHC25
        Alector, Inc.
        014442107
        
          
        
        9205.00000000
        NS
        USD
        93522.80000000
        0.175547629663
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Agios Pharmaceuticals Inc
        529900ONJHY8EOGYT555
        Agios Pharmaceuticals, Inc.
        00847X104
        
          
        
        6130.00000000
        NS
        USD
        135902.10000000
        0.255095992861
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inari Medical Inc
        N/A
        Inari Medical, Inc.
        45332Y109
        
          
        
        5773.00000000
        NS
        USD
        392506.27000000
        0.736756655343
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Esperion Therapeutics Inc
        549300OFU56UKEWVUS92
        Esperion Therapeutics, Inc.
        29664W105
        
          
        
        7048.00000000
        NS
        USD
        44825.28000000
        0.084139607165
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Precigen Inc
        549300XCWNQU35K64G19
        Precigen, Inc.
        74017N105
        
          
        
        23198.00000000
        NS
        USD
        31085.32000000
        0.058348918587
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        American Well Corp
        N/A
        American Well Corp.
        03044L105
        
          
        
        25849.00000000
        NS
        USD
        111667.68000000
        0.209606604314
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Relmada Therapeutics Inc
        549300217EASRZ9JSF81
        Relmada Therapeutics, Inc.
        75955J402
        
          
        
        3110.00000000
        NS
        USD
        59058.90000000
        0.110856923718
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        NuVasive Inc
        549300C5ZB4NZ6TWM881
        NuVasive, Inc.
        670704105
        
          
        
        5809.00000000
        NS
        USD
        285570.44000000
        0.536032003359
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Arcturus Therapeutics Holdings Inc
        N/A
        Arcturus Therapeutics Holdings, Inc.
        03969T109
        
          
        
        2957.00000000
        NS
        USD
        46543.18000000
        0.087364203445
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Intellia Therapeutics Inc
        5493002T5BCPE5DZC723
        Intellia Therapeutics, Inc.
        45826J105
        
          
        
        8524.00000000
        NS
        USD
        441202.24000000
        0.828161768403
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Turning Point Therapeutics Inc
        N/A
        Turning Point Therapeutics, Inc.
        90041T108
        
          
        
        5567.00000000
        NS
        USD
        418916.75000000
        0.786330632622
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        NGM Biopharmaceuticals Inc
        5493008V5DSDZIGQOP17
        NGM Biopharmaceuticals, Inc.
        62921N105
        
          
        
        8718.00000000
        NS
        USD
        111764.76000000
        0.209788829011
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Bluebird Bio Inc
        N/A
        Bluebird Bio, Inc.
        09609G100
        
          
        
        7866.00000000
        NS
        USD
        32565.24000000
        0.061126812835
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Marinus Pharmaceuticals Inc
        549300NCT4OJF7JV1084
        Marinus Pharmaceuticals, Inc.
        56854Q200
        
          
        
        4125.00000000
        NS
        USD
        19965.00000000
        0.037475443701
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Apellis Pharmaceuticals Inc
        254900HS0ZFRXXSB9D42
        Apellis Pharmaceuticals, Inc.
        03753U106
        
          
        
        11144.00000000
        NS
        USD
        503931.68000000
        0.945908505050
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Madrigal Pharmaceuticals Inc
        549300CHIMT2EUSNJB60
        Madrigal Pharmaceuticals, Inc.
        558868105
        
          
        
        1919.00000000
        NS
        USD
        137362.02000000
        0.257836345968
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inspire Medical Systems Inc
        549300XQQCQ7HCJKTW25
        Inspire Medical Systems, Inc.
        457730109
        
          
        
        3137.00000000
        NS
        USD
        573035.79000000
        1.075620860865
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        NRX Pharmaceuticals Inc
        5493003FN4CLS0670T77
        NRX Pharmaceuticals, Inc.
        629444100
        
          
        
        6599.00000000
        NS
        USD
        3959.40000000
        0.007432019623
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Albireo Pharma Inc
        549300835H8LC7O8VC29
        Albireo Pharma, Inc.
        01345P106
        
          
        
        2172.00000000
        NS
        USD
        43135.92000000
        0.080968582092
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ACADIA Pharmaceuticals Inc
        529900O3044NO0PEA039
        ACADIA Pharmaceuticals, Inc.
        004225108
        
          
        
        18377.00000000
        NS
        USD
        258931.93000000
        0.486030000765
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cullinan Oncology Inc
        N/A
        Cullinan Oncology, Inc.
        230031106
        
          
        
        4901.00000000
        NS
        USD
        62830.82000000
        0.117937032689
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Aerie Pharmaceuticals Inc
        529900SFXHDHUO324R09
        Aerie Pharmaceuticals, Inc.
        00771V108
        
          
        
        5430.00000000
        NS
        USD
        40725.00000000
        0.076443147746
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Viking Therapeutics Inc
        529900IVC72YPFA25M37
        Viking Therapeutics, Inc.
        92686J106
        
          
        
        8793.00000000
        NS
        USD
        25411.77000000
        0.047699341647
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        CTI BioPharma Corp
        N/A
        CTI BioPharma Corp.
        12648L601
        
          
        
        10849.00000000
        NS
        USD
        64768.53000000
        0.121574224876
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Penumbra Inc
        549300RGE06P3ECANU72
        Penumbra, Inc.
        70975L107
        
          
        
        4285.00000000
        NS
        USD
        533568.20000000
        1.001537943406
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        REVOLUTION Medicines Inc
        549300JU3X0LBCQ65892
        REVOLUTION Medicines, Inc.
        76155X100
        
          
        
        8323.00000000
        NS
        USD
        162215.27000000
        0.304487313720
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        OrthoPediatrics Corp
        5493000KUTPFGOPAT717
        OrthoPediatrics Corp.
        68752L100
        
          
        
        2215.00000000
        NS
        USD
        95577.25000000
        0.179403949488
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Endo International PLC
        5493007TBMWZWGZIB256
        Endo International PLC
        000000000
        
          
        
        26220.00000000
        NS
        USD
        12210.65000000
        0.022920086483
        Long
        EC
        CORP
        IE
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Iovance Biotherapeutics Inc
        549300220Z2GHH33XL82
        Iovance Biotherapeutics, Inc.
        462260100
        
          
        
        17635.00000000
        NS
        USD
        194690.40000000
        0.365444984946
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ORIC Pharmaceuticals Inc
        54930033FJRNEYBW0L25
        ORIC Pharmaceuticals, Inc.
        68622P109
        
          
        
        4419.00000000
        NS
        USD
        19797.12000000
        0.037160323366
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Nevro Corp
        254900SH91I4BOYKUE38
        Nevro Corp.
        64157F103
        
          
        
        3933.00000000
        NS
        USD
        172383.39000000
        0.323573454898
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Alphatec Holdings Inc
        549300EZE8CQ8K65FS24
        Alphatec Holdings, Inc.
        02081G201
        
          
        
        11196.00000000
        NS
        USD
        73221.84000000
        0.137441569879
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Mersana Therapeutics Inc
        529900VWD5VDZ7PVOS22
        Mersana Therapeutics, Inc.
        59045L106
        
          
        
        9356.00000000
        NS
        USD
        43224.72000000
        0.081135264757
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Avanos Medical Inc
        549300YCXWOM7NEWMQ58
        Avanos Medical, Inc.
        05350V106
        
          
        
        5309.00000000
        NS
        USD
        145148.06000000
        0.272451187124
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Recursion Pharmaceuticals Inc
        N/A
        Recursion Pharmaceuticals, Inc.
        75629V104
        
          
        
        17900.00000000
        NS
        USD
        145706.00000000
        0.273498472326
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Celldex Therapeutics Inc
        529900F018DMYWH38923
        Celldex Therapeutics, Inc.
        15117B202
        
          
        
        5243.00000000
        NS
        USD
        141351.28000000
        0.265324414515
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cassava Sciences Inc
        529900XA0UG5JXABYF08
        Cassava Sciences, Inc.
        14817C107
        
          
        
        4490.00000000
        NS
        USD
        126258.80000000
        0.236994968757
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Amneal Pharmaceuticals Inc
        549300VV176ZO5WQHZ61
        Amneal Pharmaceuticals, Inc.
        03168L105
        
          
        
        16766.00000000
        NS
        USD
        53315.88000000
        0.100076947625
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ImmunoGen Inc
        54930084U0R1OP766Y02
        ImmunoGen, Inc.
        45253H101
        
          
        
        24745.00000000
        NS
        USD
        111352.50000000
        0.209014993478
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        MEI Pharma Inc
        529900A43X33ON524197
        MEI Pharma, Inc.
        55279B202
        
          
        
        14921.00000000
        NS
        USD
        9027.21000000
        0.016944588035
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Provention Bio Inc
        5493003LM26XAVJKLD34
        Provention Bio, Inc.
        74374N102
        
          
        
        7110.00000000
        NS
        USD
        28440.00000000
        0.053383502072
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        AngioDynamics Inc
        549300W3VKC5ZKMO8C28
        AngioDynamics, Inc.
        03475V101
        
          
        
        4344.00000000
        NS
        USD
        84056.40000000
        0.157778656947
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Twist Bioscience Corp
        549300T23BL59LCOH584
        Twist Bioscience Corp.
        90184D100
        
          
        
        6295.00000000
        NS
        USD
        220073.20000000
        0.413089948251
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        CRISPR Therapeutics AG
        506700O6IRRIQLT3W370
        CRISPR Therapeutics AG
        000000000
        
          
        
        8794.00000000
        NS
        USD
        534411.38000000
        1.003120640356
        Long
        EC
        CORP
        CH
        N
        
        1
        
          N
          N
          N
        
      
      
        Enanta Pharmaceuticals Inc
        529900SSN4DODDQSN594
        Enanta Pharmaceuticals, Inc.
        29251M106
        
          
        
        2304.00000000
        NS
        USD
        108910.08000000
        0.204430431834
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Bioxcel Therapeutics Inc
        549300Y25FYZ0E8LW260
        Bioxcel Therapeutics, Inc.
        09075P105
        
          
        
        3139.00000000
        NS
        USD
        41434.80000000
        0.077775482829
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Denali Therapeutics Inc
        549300ZTQ2HO18L3Q830
        Denali Therapeutics, Inc.
        24823R105
        
          
        
        14045.00000000
        NS
        USD
        413344.35000000
        0.775870920001
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sutro Biopharma Inc
        5493005U6P15VD25P851
        Sutro Biopharma, Inc.
        869367102
        
          
        
        5204.00000000
        NS
        USD
        27112.84000000
        0.050892347057
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Kiniksa Pharmaceuticals Ltd
        N/A
        Kiniksa Pharmaceuticals Ltd.
        000000000
        
          
        
        3826.00000000
        NS
        USD
        37073.94000000
        0.069589899888
        Long
        EC
        CORP
        BM
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Mirati Therapeutics Inc
        529900GYRW59IDQV6N54
        Mirati Therapeutics, Inc.
        60468T105
        
          
        
        6336.00000000
        NS
        USD
        425335.68000000
        0.798379330335
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sana Biotechnology Inc
        N/A
        Sana Biotechnology, Inc.
        799566104
        
          
        
        21189.00000000
        NS
        USD
        136245.27000000
        0.255740142524
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Eargo Inc
        N/A
        Eargo, Inc.
        270087109
        
          
        
        4410.00000000
        NS
        USD
        3315.88000000
        0.006224095880
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        SomaLogic Inc
        549300D3W3Q8CN30YO25
        SomaLogic, Inc.
        83444K105
        
          
        
        20329.00000000
        NS
        USD
        91887.08000000
        0.172477289929
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cara Therapeutics Inc
        549300COVOY41P0GZ881
        Cara Therapeutics, Inc.
        140755109
        
          
        
        5997.00000000
        NS
        USD
        54752.61000000
        0.102773771779
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Akero Therapeutics Inc
        549300SI3KG74LBE2955
        Akero Therapeutics, Inc.
        00973Y108
        
          
        
        3929.00000000
        NS
        USD
        37129.05000000
        0.069693344501
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cerevel Therapeutics Holdings Inc
        N/A
        Cerevel Therapeutics Holdings, Inc.
        15678U128
        
          
        
        16877.00000000
        NS
        USD
        446227.88000000
        0.837595181320
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        TransMedics Group Inc
        N/A
        TransMedics Group, Inc.
        89377M109
        
          
        
        3137.00000000
        NS
        USD
        98658.65000000
        0.185187913035
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inovio Pharmaceuticals Inc
        529900B9W875XDZXTM97
        Inovio Pharmaceuticals, Inc.
        45773H201
        
          
        
        23607.00000000
        NS
        USD
        40840.11000000
        0.076659215781
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Health Catalyst Inc
        549300223PL6GWKVJG92
        Health Catalyst, Inc.
        42225T107
        
          
        
        5986.00000000
        NS
        USD
        86737.14000000
        0.162810558823
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Guardant Health Inc
        254900M8C3E5VC8BR186
        Guardant Health, Inc.
        40131M109
        
          
        
        11594.00000000
        NS
        USD
        467701.96000000
        0.877903254251
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Axsome Therapeutics Inc
        549300EXGR0XLRJEIB95
        Axsome Therapeutics, Inc.
        05464T104
        
          
        
        4228.00000000
        NS
        USD
        161932.40000000
        0.303956350597
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Tabula Rasa HealthCare Inc
        549300K6KY242XRMEF28
        Tabula Rasa HealthCare, Inc.
        873379101
        
          
        
        2887.00000000
        NS
        USD
        7419.59000000
        0.013926993605
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ImmunityBio Inc
        529900J9XLBR4HFL4B83
        ImmunityBio, Inc.
        45256X103
        
          
        
        44636.00000000
        NS
        USD
        166045.92000000
        0.311677662251
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Vaxart Inc
        N/A
        Vaxart, Inc.
        92243A200
        
          
        
        14116.00000000
        NS
        USD
        49406.00000000
        0.092737879866
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Precision BioSciences Inc
        549300I5QGRS3BLHZH41
        Precision BioSciences, Inc.
        74019P108
        
          
        
        6817.00000000
        NS
        USD
        10907.20000000
        0.020473436491
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Intra-Cellular Therapies Inc
        5299002U2KGF193IJA20
        Intra-Cellular Therapies, Inc.
        46116X101
        
          
        
        10531.00000000
        NS
        USD
        601109.48000000
        1.128316778175
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Quantum-Si Inc
        N/A
        Quantum-Si, Inc.
        74765K105
        
          
        
        13182.00000000
        NS
        USD
        30582.24000000
        0.057404608734
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Ginkgo Bioworks Holdings Inc
        N/A
        Ginkgo Bioworks Holdings, Inc.
        37611X100
        
          
        
        135751.00000000
        NS
        USD
        323087.38000000
        0.606453439514
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Pulmonx Corp
        549300WZMFR0ZK7RJY40
        Pulmonx Corp.
        745848101
        
          
        
        4153.00000000
        NS
        USD
        61132.16000000
        0.114748550986
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Perrigo Co PLC
        549300IFOQS6R1QLY196
        Perrigo Co. PLC
        000000000
        
          
        
        15248.00000000
        NS
        USD
        618611.36000000
        1.161168805153
        Long
        EC
        CORP
        IE
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Nuvation Bio Inc
        N/A
        Nuvation Bio, Inc.
        67080N101
        
          
        
        24437.00000000
        NS
        USD
        79175.88000000
        0.148617642547
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Krystal Biotech Inc
        549300YONUY68210OE41
        Krystal Biotech, Inc.
        501147102
        
          
        
        2827.00000000
        NS
        USD
        185620.82000000
        0.348420866003
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Reata Pharmaceuticals Inc
        5299005F094GH9QDDD80
        Reata Pharmaceuticals, Inc.
        75615P103
        
          
        
        3532.00000000
        NS
        USD
        107337.48000000
        0.201478571941
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ADMA Biologics Inc
        N/A
        ADMA Biologics, Inc.
        000899104
        
          
        
        21972.00000000
        NS
        USD
        43504.56000000
        0.081660540397
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Fate Therapeutics Inc
        549300L14Q4UHOODLA90
        Fate Therapeutics, Inc.
        31189P102
        
          
        
        10818.00000000
        NS
        USD
        268070.04000000
        0.503182754426
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Hims & Hers Health Inc
        549300ZQ4ZUYSAAX6P59
        Hims & Hers Health, Inc.
        433000106
        
          
        
        22071.00000000
        NS
        USD
        99981.63000000
        0.187671221951
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Ideaya Biosciences Inc
        549300ULW08F62IJML11
        Ideaya Biosciences, Inc.
        45166A102
        
          
        
        4320.00000000
        NS
        USD
        59616.00000000
        0.111902632192
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Butterfly Network Inc
        N/A
        Butterfly Network, Inc.
        124155102
        
          
        
        19269.00000000
        NS
        USD
        59155.83000000
        0.111038866856
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Karuna Therapeutics Inc
        N/A
        Karuna Therapeutics, Inc.
        48576A100
        
          
        
        3405.00000000
        NS
        USD
        430766.55000000
        0.808573383074
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Avidity Biosciences Inc
        N/A
        Avidity Biosciences, Inc.
        05370A108
        
          
        
        5262.00000000
        NS
        USD
        76456.86000000
        0.143513886928
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Allakos Inc
        549300S6ZD1W6BPMDY37
        Allakos, Inc.
        01671P100
        
          
        
        6094.00000000
        NS
        USD
        19074.22000000
        0.035803398836
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cortexyme Inc
        N/A
        Cortexyme, Inc.
        22053A107
        
          
        
        3374.00000000
        NS
        USD
        7490.28000000
        0.014059682767
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Replimune Group Inc
        549300AY704NEIRC4K64
        Replimune Group, Inc.
        76029N106
        
          
        
        5297.00000000
        NS
        USD
        92591.56000000
        0.173799639069
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        NanoString Technologies Inc
        549300G4CK0Y3WRDMY89
        NanoString Technologies, Inc.
        63009R109
        
          
        
        5121.00000000
        NS
        USD
        65036.70000000
        0.122077595261
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Phreesia Inc
        5493000HHF8NU4QOCG53
        Phreesia, Inc.
        71944F106
        
          
        
        5749.00000000
        NS
        USD
        143782.49000000
        0.269887934349
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        IGM Biosciences Inc
        5493008XCQES2N0VY969
        IGM Biosciences, Inc.
        449585108
        
          
        
        2921.00000000
        NS
        USD
        52665.63000000
        0.098856391288
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Surgery Partners Inc
        549300LC82HG33S19I03
        Surgery Partners, Inc.
        86881A100
        
          
        
        10186.00000000
        NS
        USD
        294579.12000000
        0.552941809529
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Veracyte Inc
        529900ESWZRHXOW27Z37
        Veracyte, Inc.
        92337F107
        
          
        
        7991.00000000
        NS
        USD
        159020.90000000
        0.298491299040
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Atea Pharmaceuticals Inc
        N/A
        Atea Pharmaceuticals, Inc.
        04683R106
        
          
        
        9338.00000000
        NS
        USD
        66299.80000000
        0.124448506002
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Privia Health Group Inc
        N/A
        Privia Health Group, Inc.
        74276R102
        
          
        
        11949.00000000
        NS
        USD
        347954.88000000
        0.653131155329
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Vaxcyte Inc
        254900M7NMHTGASX8D95
        Vaxcyte, Inc.
        92243G108
        
          
        
        6318.00000000
        NS
        USD
        137479.68000000
        0.258057200499
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ViewRay Inc
        5493006XTUBSKFU3W106
        ViewRay, Inc.
        92672L107
        
          
        
        20130.00000000
        NS
        USD
        53344.50000000
        0.100130668997
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Quanterix Corp
        N/A
        Quanterix Corp.
        74766Q101
        
          
        
        4134.00000000
        NS
        USD
        66929.46000000
        0.125630413734
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sorrento Therapeutics Inc
        549300RH23PRR3M13410
        Sorrento Therapeutics, Inc.
        83587F202
        
          
        
        41024.00000000
        NS
        USD
        82458.24000000
        0.154778819477
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Blueprint Medicines Corp
        5299004CC60O9T5HVM83
        Blueprint Medicines Corp.
        09627Y109
        
          
        
        6760.00000000
        NS
        USD
        341447.60000000
        0.640916619627
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Morphic Holding Inc
        549300RWWOUFLHTY1224
        Morphic Holding, Inc.
        61775R105
        
          
        
        4162.00000000
        NS
        USD
        90315.40000000
        0.169527156929
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Rigel Pharmaceuticals Inc
        529900KPTNUS5J8K9K66
        Rigel Pharmaceuticals, Inc.
        766559603
        
          
        
        19188.00000000
        NS
        USD
        21682.44000000
        0.040699176535
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        CareDx Inc
        549300NQOFKL9NON0U06
        CareDx, Inc.
        14167L103
        
          
        
        5949.00000000
        NS
        USD
        127784.52000000
        0.239858832216
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Bridgebio Pharma Inc
        54930028YG89VTY2J114
        Bridgebio Pharma, Inc.
        10806X102
        
          
        
        16562.00000000
        NS
        USD
        150382.96000000
        0.282277392996
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        BioAtla Inc
        N/A
        BioAtla, Inc.
        09077B104
        
          
        
        4020.00000000
        NS
        USD
        11457.00000000
        0.021505442448
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Prothena Corp PLC
        5299009ZXQ8NIIJ8OL30
        Prothena Corp. PLC
        000000000
        
          
        
        5237.00000000
        NS
        USD
        142184.55000000
        0.266888509830
        Long
        EC
        CORP
        IE
        N
        
        1
        
          N
          N
          N
        
      
      
        Heska Corp
        529900O1OR2EB7L0HY27
        Heska Corp.
        42805E306
        
          
        
        1211.00000000
        NS
        USD
        114451.61000000
        0.214832199705
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Kodiak Sciences Inc
        254900IXI5NI8C9OQE24
        Kodiak Sciences, Inc.
        50015M109
        
          
        
        5801.00000000
        NS
        USD
        44319.64000000
        0.083190492045
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        MacroGenics Inc
        5493001KJQUA83L8MH79
        MacroGenics, Inc.
        556099109
        
          
        
        6880.00000000
        NS
        USD
        20296.00000000
        0.038096749580
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Kymera Therapeutics Inc
        N/A
        Kymera Therapeutics, Inc.
        501575104
        
          
        
        5801.00000000
        NS
        USD
        114221.69000000
        0.214400626752
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Stoke Therapeutics Inc
        549300RD25SS2DIJHJ67
        Stoke Therapeutics, Inc.
        86150R107
        
          
        
        4128.00000000
        NS
        USD
        54530.88000000
        0.102357571922
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Dynavax Technologies Corp
        549300T5URIXWDILX594
        Dynavax Technologies Corp.
        268158201
        
          
        
        14016.00000000
        NS
        USD
        176461.44000000
        0.331228187339
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Seer Inc
        N/A
        Seer, Inc.
        81578P106
        
          
        
        6397.00000000
        NS
        USD
        57253.15000000
        0.107467427977
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Deciphera Pharmaceuticals Inc
        529900QR4WAPYY0CBF25
        Deciphera Pharmaceuticals, Inc.
        24344T101
        
          
        
        6570.00000000
        NS
        USD
        86395.50000000
        0.162169281058
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cue Health Inc
        N/A
        Cue Health, Inc.
        229790100
        
          
        
        16424.00000000
        NS
        USD
        52556.80000000
        0.098652111171
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        IVERIC bio Inc
        549300GZXI59U71XPM70
        IVERIC bio, Inc.
        46583P102
        
          
        
        12979.00000000
        NS
        USD
        124857.98000000
        0.234365549721
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Global Blood Therapeutics Inc
        549300U4G0QKK99GRT15
        Global Blood Therapeutics, Inc.
        37890U108
        
          
        
        7272.00000000
        NS
        USD
        232340.40000000
        0.436116182310
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        iTeos Therapeutics Inc
        N/A
        iTeos Therapeutics, Inc.
        46565G104
        
          
        
        3957.00000000
        NS
        USD
        81514.20000000
        0.153006802553
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Shockwave Medical Inc
        549300LDXO56IC5Y1538
        Shockwave Medical, Inc.
        82489T104
        
          
        
        4060.00000000
        NS
        USD
        776150.20000000
        1.456878193044
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Jazz Pharmaceuticals PLC
        635400GAUMJCLEZRRV50
        Jazz Pharmaceuticals PLC
        000000000
        
          
        
        6987.00000000
        NS
        USD
        1090041.87000000
        2.046070760413
        Long
        EC
        CORP
        IE
        
        N
        
        1
        
          N
          N
          N
        
      
      
        TG Therapeutics Inc
        529900X21UKABN9NJ529
        TG Therapeutics, Inc.
        88322Q108
        
          
        
        16025.00000000
        NS
        USD
        68106.25000000
        0.127839315682
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sarepta Therapeutics Inc
        549300IKDPIED8J8IG21
        Sarepta Therapeutics, Inc.
        803607100
        
          
        
        9912.00000000
        NS
        USD
        743003.52000000
        1.394659984167
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Aldeyra Therapeutics Inc
        529900HGKY864E4Y9014
        Aldeyra Therapeutics, Inc.
        01438T106
        
          
        
        6518.00000000
        NS
        USD
        26006.82000000
        0.048816284436
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        1Life Healthcare Inc
        N/A
        1Life Healthcare, Inc.
        68269G107
        
          
        
        21555.00000000
        NS
        USD
        168991.20000000
        0.317206120795
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        FibroGen Inc
        549300Q914ULWWY95822
        FibroGen, Inc.
        31572Q808
        
          
        
        10435.00000000
        NS
        USD
        110193.60000000
        0.206839672080
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Gossamer Bio Inc
        549300ZOC0N2W6PSFR58
        Gossamer Bio, Inc.
        38341P102
        
          
        
        8579.00000000
        NS
        USD
        71806.23000000
        0.134784389170
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Sangamo Therapeutics Inc
        2549006WMRKRC4G32Z67
        Sangamo Therapeutics, Inc.
        800677106
        
          
        
        16378.00000000
        NS
        USD
        67804.92000000
        0.127273702086
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        SmileDirectClub Inc
        254900QFZEGKCURCJS93
        SmileDirectClub, Inc.
        83192H106
        
          
        
        13504.00000000
        NS
        USD
        14044.16000000
        0.026361689327
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Xeris Biopharma Holdings Inc
        N/A
        Xeris Biopharma Holdings, Inc.
        98422E103
        
          
        
        15160.00000000
        NS
        USD
        23346.40000000
        0.043822524359
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Heron Therapeutics Inc
        549300DR2I1DOPD2IX53
        Heron Therapeutics, Inc.
        427746102
        
          
        
        11460.00000000
        NS
        USD
        31973.40000000
        0.060015895399
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        NeoGenomics Inc
        N/A
        NeoGenomics, Inc.
        64049M209
        
          
        
        13916.00000000
        NS
        USD
        113415.40000000
        0.212887174435
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Ultragenyx Pharmaceutical Inc
        529900EV44GVDN1DCX77
        Ultragenyx Pharmaceutical, Inc.
        90400D108
        
          
        
        7906.00000000
        NS
        USD
        471671.96000000
        0.885355170680
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Oak Street Health Inc
        2549007CJE6GSEURLA30
        Oak Street Health, Inc.
        67181A107
        
          
        
        27449.00000000
        NS
        USD
        451261.56000000
        0.847043685775
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Insmed Inc
        529900Q55QAG41CCAC11
        Insmed, Inc.
        457669307
        
          
        
        13342.00000000
        NS
        USD
        263104.24000000
        0.493861664602
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        RAPT Therapeutics Inc
        549300MB473BIU78ES48
        RAPT Therapeutics, Inc.
        75382E109
        
          
        
        3315.00000000
        NS
        USD
        60498.75000000
        0.113559604289
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Arcus Biosciences Inc
        N/A
        Arcus Biosciences, Inc.
        03969F109
        
          
        
        7973.00000000
        NS
        USD
        202035.82000000
        0.379232757231
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Arcutis Biotherapeutics Inc
        N/A
        Arcutis Biotherapeutics, Inc.
        03969K108
        
          
        
        5652.00000000
        NS
        USD
        120444.12000000
        0.226080482757
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Vir Biotechnology Inc
        N/A
        Vir Biotechnology, Inc.
        92764N102
        
          
        
        14845.00000000
        NS
        USD
        378102.15000000
        0.709719300566
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Vericel Corp
        54930076YM3PLTDR4B91
        Vericel Corp.
        92346J108
        
          
        
        5277.00000000
        NS
        USD
        132874.86000000
        0.249413690723
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Radius Health Inc
        549300EV6I2M6E0YVT27
        Radius Health, Inc.
        750469207
        
          
        
        5316.00000000
        NS
        USD
        55126.92000000
        0.103476372998
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Harmony Biosciences Holdings Inc
        N/A
        Harmony Biosciences Holdings, Inc.
        413197104
        
          
        
        6605.00000000
        NS
        USD
        322125.85000000
        0.604648592863
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Silk Road Medical Inc
        549300VL8KC0ZPDQHE14
        Silk Road Medical, Inc.
        82710M100
        
          
        
        3929.00000000
        NS
        USD
        142976.31000000
        0.268374688508
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Principal Government Money Market Fund
        549300WWK3YB7DNN4U34
        Principal Government Money Market Fund
        000000000
        
          
        
        1097186.75000000
        NS
        USD
        1097186.75000000
        2.059482107680
        Long
        STIV
        RF
        US
        N
        
        1
        
          
          N
          N
        
      
      
        RadNet Inc
        529900RECG94V2IZJ970
        RadNet, Inc.
        750491102
        
          
        
        6304.00000000
        NS
        USD
        108933.12000000
        0.204473679229
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Arvinas Inc
        N/A
        Arvinas, Inc.
        04335A105
        
          
        
        5953.00000000
        NS
        USD
        250561.77000000
        0.470318733054
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Altimmune Inc
        549300EOYCQ8SW3NVE64
        Altimmune, Inc.
        02155H200
        
          
        
        4458.00000000
        NS
        USD
        52158.60000000
        0.097904667060
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        ALX Oncology Holdings Inc
        N/A
        ALX Oncology Holdings, Inc.
        00166B105
        
          
        
        4558.00000000
        NS
        USD
        36874.22000000
        0.069215014057
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Natera Inc
        N/A
        Natera, Inc.
        632307104
        
          
        
        10904.00000000
        NS
        USD
        386437.76000000
        0.725365715956
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Neurocrine Biosciences Inc
        549300FECER0XBN49756
        Neurocrine Biosciences, Inc.
        64125C109
        
          
        
        10830.00000000
        NS
        USD
        1055708.40000000
        1.981624879017
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Bright Health Group Inc
        N/A
        Bright Health Group, Inc.
        10920V107
        
          
        
        70552.00000000
        NS
        USD
        128404.64000000
        0.241022832825
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        HealthEquity Inc
        529900LRJU1RAFQHM467
        HealthEquity, Inc.
        42226A107
        
          
        
        9524.00000000
        NS
        USD
        584678.36000000
        1.097474628788
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Standard BioTools Inc
        549300GX8Y96GSB6YP89
        Standard BioTools, Inc.
        34385P108
        
          
        
        8662.00000000
        NS
        USD
        13859.20000000
        0.026014508858
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Editas Medicine Inc
        5299000AON4Q9NT2JE42
        Editas Medicine, Inc.
        28106W103
        
          
        
        7688.00000000
        NS
        USD
        90949.04000000
        0.170716535348
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Bionano Genomics Inc
        54930086AP7ROH0VJ631
        Bionano Genomics, Inc.
        09075F107
        
          
        
        32497.00000000
        NS
        USD
        44845.86000000
        0.084178236998
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Forma Therapeutics Holdings Inc
        N/A
        Forma Therapeutics Holdings, Inc.
        34633R104
        
          
        
        5318.00000000
        NS
        USD
        36641.02000000
        0.068777284356
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Certara Inc
        N/A
        Certara, Inc.
        15687V109
        
          
        
        18252.00000000
        NS
        USD
        391687.92000000
        0.735220565719
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Lantheus Holdings Inc
        5299005HUB5IOJGO7S39
        Lantheus Holdings, Inc.
        516544103
        
          
        
        7763.00000000
        NS
        USD
        512590.89000000
        0.962162336097
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Outset Medical Inc
        N/A
        Outset Medical, Inc.
        690145107
        
          
        
        5319.00000000
        NS
        USD
        79040.34000000
        0.148363226237
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cytokinetics Inc
        549300BE5DY1HW7IHA64
        Cytokinetics, Inc.
        23282W605
        
          
        
        9690.00000000
        NS
        USD
        380720.10000000
        0.714633342030
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Chimerix Inc
        5299002IR2GXUBEPKS66
        Chimerix, Inc.
        16934W106
        
          
        
        9746.00000000
        NS
        USD
        20271.68000000
        0.038051099553
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inhibrx Inc
        549300VBKG2LTV1TLY22
        Inhibrx, Inc.
        45720L107
        
          
        
        4378.00000000
        NS
        USD
        49690.30000000
        0.093271527181
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Ocular Therapeutix Inc
        529900ABAWFXOHSIHG03
        Ocular Therapeutix, Inc.
        67576A100
        
          
        
        8612.00000000
        NS
        USD
        34620.24000000
        0.064984165041
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Inotiv Inc
        549300FH5Z13X0Q5SK81
        Inotiv, Inc.
        45783Q100
        
          
        
        2856.00000000
        NS
        USD
        27417.60000000
        0.051464398959
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Nurix Therapeutics Inc
        N/A
        Nurix Therapeutics, Inc.
        67080M103
        
          
        
        5019.00000000
        NS
        USD
        63590.73000000
        0.119363427100
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Syndax Pharmaceuticals Inc
        529900OF94TRHKZVBS87
        Syndax Pharmaceuticals, Inc.
        87164F105
        
          
        
        5896.00000000
        NS
        USD
        113439.04000000
        0.212931548063
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        OPKO Health Inc
        529900A4S2D4OGOJLL02
        OPKO Health, Inc.
        68375N103
        
          
        
        76466.00000000
        NS
        USD
        193458.98000000
        0.363133539372
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        REGENXBIO Inc
        549300EOES47LATSET33
        REGENXBIO, Inc.
        75901B107
        
          
        
        4798.00000000
        NS
        USD
        118510.60000000
        0.222451155439
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Immunovant Inc
        N/A
        Immunovant, Inc.
        45258J102
        
          
        
        13060.00000000
        NS
        USD
        50934.00000000
        0.095606023015
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Biohaven Pharmaceutical Holding Co Ltd
        5299007STZTNN32O9920
        Biohaven Pharmaceutical Holding Co. Ltd.
        000000000
        
          
        
        8028.00000000
        NS
        USD
        1169759.88000000
        2.195706011891
        Long
        EC
        CORP
        VG
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Glaukos Corp
        5299004JA1LHE21M6T14
        Glaukos Corp.
        377322102
        
          
        
        5278.00000000
        NS
        USD
        239726.76000000
        0.449980801310
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Cerus Corp
        254900BIEY9XIDA04Q21
        Cerus Corp.
        157085101
        
          
        
        19493.00000000
        NS
        USD
        103117.97000000
        0.193558311012
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Rocket Pharmaceuticals Inc
        549300R7VV82YUIN4Y93
        Rocket Pharmaceuticals, Inc.
        77313F106
        
          
        
        7238.00000000
        NS
        USD
        99594.88000000
        0.186945270143
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Atara Biotherapeutics Inc
        549300WBXUXZRE03MS38
        Atara Biotherapeutics, Inc.
        046513107
        
          
        
        10445.00000000
        NS
        USD
        81366.55000000
        0.152729655082
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        EQRx Inc
        N/A
        EQRx, Inc.
        26886C107
        
          
        
        52751.00000000
        NS
        USD
        247402.19000000
        0.464388021187
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Artivion Inc
        549300YTKV8DMSMG6K81
        Artivion, Inc.
        228903100
        
          
        
        4500.00000000
        NS
        USD
        84960.00000000
        0.159474765684
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Coherus Biosciences Inc
        5493007IL8W5MV932D26
        Coherus Biosciences, Inc.
        19249H103
        
          
        
        8670.00000000
        NS
        USD
        62770.80000000
        0.117824371725
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Personalis Inc
        549300EZ2NYFK7H0US48
        Personalis, Inc.
        71535D106
        
          
        
        5043.00000000
        NS
        USD
        17398.35000000
        0.032657695263
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Applied Molecular Transport Inc
        N/A
        Applied Molecular Transport, Inc.
        03824M109
        
          
        
        4336.00000000
        NS
        USD
        12617.76000000
        0.023684255172
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Alkermes PLC
        N/A
        Alkermes PLC
        000000000
        
          
        
        18459.00000000
        NS
        USD
        549893.61000000
        1.032181669094
        Long
        EC
        CORP
        IE
        
        N
        
        1
        
          N
          N
          N
        
      
      
        Elanco Animal Health Inc
        549300SHPNDCE059M934
        Elanco Animal Health, Inc.
        28414H103
        
          
        
        53757.00000000
        NS
        USD
        1055249.91000000
        1.980764267137
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Amicus Therapeutics Inc
        549300MRD1SMUTNBPQ53
        Amicus Therapeutics, Inc.
        03152W109
        
          
        
        31424.00000000
        NS
        USD
        337493.76000000
        0.633495036441
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Codexis Inc
        N/A
        Codexis, Inc.
        192005106
        
          
        
        7310.00000000
        NS
        USD
        76462.60000000
        0.143524661236
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Accolade Inc
        549300PHKG8J7A22NF08
        Accolade, Inc.
        00437E102
        
          
        
        7513.00000000
        NS
        USD
        55596.20000000
        0.104357238323
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        PROCEPT BioRobotics Corp
        N/A
        PROCEPT BioRobotics Corp.
        74276L105
        
          
        
        4880.00000000
        NS
        USD
        159527.20000000
        0.299441653017
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        Clover Health Investments Corp
        5493000HLYOYQU6LK133
        Clover Health Investments Corp.
        18914F103
        
          
        
        42475.00000000
        NS
        USD
        90896.50000000
        0.170617914772
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
      
        C4 Therapeutics Inc
        N/A
        C4 Therapeutics, Inc.
        12529R107
        
          
        
        5468.00000000
        NS
        USD
        41228.72000000
        0.077388658915
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Scholar Rock Holding Corp
        549300Z1FLPGL4OWJ459
        Scholar Rock Holding Corp.
        80706P103
        
          
        
        3937.00000000
        NS
        USD
        21614.13000000
        0.040570954769
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        PTC Therapeutics Inc
        549300UJLWOIWFDGB318
        PTC Therapeutics, Inc.
        69366J200
        
          
        
        8008.00000000
        NS
        USD
        320800.48000000
        0.602160797781
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Novavax Inc
        529900J4GJHPEPQ23205
        Novavax, Inc.
        670002401
        
          
        
        8634.00000000
        NS
        USD
        444046.62000000
        0.833500831892
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Evolus Inc
        549300VYQRYBQOT8V419
        Evolus, Inc.
        30052C107
        
          
        
        6235.00000000
        NS
        USD
        72326.00000000
        0.135760027105
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Karyopharm Therapeutics Inc
        549300J1VANRCNTYST87
        Karyopharm Therapeutics, Inc.
        48576U106
        
          
        
        8476.00000000
        NS
        USD
        38226.76000000
        0.071753808779
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        SpringWorks Therapeutics Inc
        N/A
        SpringWorks Therapeutics, Inc.
        85205L107
        
          
        
        5536.00000000
        NS
        USD
        136296.32000000
        0.255835966286
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        uniQure NV
        724500RPCTZLFYJZ3S98
        uniQure NV
        000000000
        
          
        
        5212.00000000
        NS
        USD
        97151.68000000
        0.182359244395
        Long
        EC
        CORP
        NL
        N
        
        1
        
          N
          N
          N
        
      
      
        Castle Biosciences Inc
        N/A
        Castle Biosciences, Inc.
        14843C105
        
          
        
        2851.00000000
        NS
        USD
        62579.45000000
        0.117465196862
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        State Street Global Advisors
        549300BZ5TGIFZUZDZ37
        State Street Institutional U.S. Government Money Market Fund
        857492706
        
          
        
        175918.87000000
        NS
        USD
        175918.87000000
        0.330209752504
        Long
        STIV
        RF
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Fulcrum Therapeutics Inc
        N/A
        Fulcrum Therapeutics, Inc.
        359616109
        
          
        
        4550.00000000
        NS
        USD
        22295.00000000
        0.041848986592
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Xencor Inc
        549300V5IF65437JKG30
        Xencor, Inc.
        98401F105
        
          
        
        6661.00000000
        NS
        USD
        182311.57000000
        0.342209215011
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Atossa Therapeutics Inc
        549300QRKP1JTNHD2366
        Atossa Therapeutics, Inc.
        04962H506
        
          
        
        14207.00000000
        NS
        USD
        15485.63000000
        0.029067410731
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Allogene Therapeutics Inc
        N/A
        Allogene Therapeutics, Inc.
        019770106
        
          
        
        16017.00000000
        NS
        USD
        182593.80000000
        0.342738976818
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Gritstone bio Inc
        5493003TER6KY3MUVY84
        Gritstone bio, Inc.
        39868T105
        
          
        
        7628.00000000
        NS
        USD
        18459.76000000
        0.034650022370
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Agenus Inc
        529900NDQQGU5H4UJK81
        Agenus, Inc.
        00847G705
        
          
        
        28854.00000000
        NS
        USD
        55976.76000000
        0.105071571148
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        MannKind Corp
        213800GFBCNY1ZFST722
        MannKind Corp.
        56400P706
        
          
        
        28253.00000000
        NS
        USD
        107643.93000000
        0.202053796070
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        Zentalis Pharmaceuticals Inc
        N/A
        Zentalis Pharmaceuticals, Inc.
        98943L107
        
          
        
        5112.00000000
        NS
        USD
        143647.20000000
        0.269633987302
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          N
        
      
      
        CEL-SCI Corp
        549300FIWOFSETIVMI17
        CEL-SCI Corp.
        150837607
        
          
        
        4854.00000000
        NS
        USD
        21843.00000000
        0.041000556813
        Long
        EC
        CORP
        US
        N
        
        1
        
          N
          N
          
        
      
    
    
      
      
    
    
      2022-07-19
      Principal Exchange-Traded Funds
      Megan Hoffmann
      Megan Hoffmann
      Vice President and Controller
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