Form 497J NUVEEN INVESTMENT TRUST

Filed pursuant to Rule 497(j)

Registration Nos. 333-33607 and 811-08333

[ON CHAPMAN AND CUTLER LLP LETTERHEAD]

November 30, 2022

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Ladies and Gentlemen:

On behalf of the Registrant, in accordance with the provisions of Rule 497(j) of Regulation C under the Securities Act of 1933 (the “Securities Act”), this letter serves to certify that the most recent amendment to the Registration Statement on Form N-1A (the “Registration Statement”) of the Registrant and its series, Nuveen Dividend Growth Fund, Nuveen Global Dividend Growth Fund, Nuveen International Dividend Growth Fund, Nuveen International Small Cap Fund and Nuveen Winslow Large-Cap Growth ESG Fund, does not differ from that which would have been filed pursuant to Rule 497(c) of the Securities Act. Post-Effective Amendment No. 198, which was the most recent amendment to the Registration Statement, was filed electronically with the Securities and Exchange Commission on November 28, 2022.

If you have any questions or comments, please telephone the undersigned at (312) 845-3484.

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