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Form 13F-HR Soleus Capital Managemen For: Jun 30

August 15, 2022 2:43 PM EDT

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The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

Report for the Calendar Year or Quarter Ended: 06-30-2022
Check here if Amendment   Amendment Number:
This Amendment (Check only one.):   is a restatement.
  adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name: Soleus Capital Management, L.P.
Address: 104 FIELD POINT ROAD
FLOOR 2
GREENWICH , CT06830
Form 13F File Number: 028-20043

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:
Name: Steven J. Musumeci
Title: Chief Operating Officer, Soleus Capital Management, L.P.
Phone: (475) 208-3111
Signature, Place, and Date of Signing:
/s/ Steven J. Musumeci Greenwich , CT 08-15-2022
[Signature] [City, State] [Date]
Report Type (Check only one.):
X 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)
  13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)
  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)
Form 13F Summary Page
Report Summary:
Number of Other Included Managers: 0
Form 13F Information Table Entry Total: 74
Form 13F Information Table Value Total: 640,262
(thousands)
List of Other Managers Reporting for this Manager:
[If there are no entries in this list, omit this section.]
Form 13F File Number Name

List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]
No. Form 13F File Number Name

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 2,932 20,100 SH SOLE 20,100 0 0
ANAPTYSBIO INC COM 032724106 13,065 643,575 SH SOLE 643,575 0 0
ANGIODYNAMICS INC COM 03475V101 12,965 670,000 SH SOLE 670,000 0 0
APOLLO ENDOSURGERY INC COM 03767D108 11,932 3,268,948 SH SOLE 3,268,948 0 0
ARCELLX INC COMMON STOCK 03940C100 16,448 909,739 SH SOLE 909,739 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 11,212 169,696 SH SOLE 169,696 0 0
BIOATLA INC COM 09077B104 9,299 3,262,703 SH SOLE 3,262,703 0 0
BRIDGEBIO PHARMA INC NOTE 2.500% 3/1 10806XAB8 1,068 1,950,000 PRN SOLE 1,950,000 0 0
C4 THERAPEUTICS INC COM STK 12529R107 2,131 282,640 SH SOLE 282,640 0 0
CELCUITY INC COM 15102K100 3,812 418,912 SH SOLE 418,912 0 0
CHEMOCENTRYX INC COM 16383L106 3,826 154,400 SH SOLE 154,400 0 0
CHINOOK THERAPEUTICS INC COM 16961L106 1,539 88,000 SH SOLE 88,000 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 1,337 22,000 SH SOLE 22,000 0 0
CULLINAN ONCOLOGY INC COM 230031106 1,224 95,485 SH SOLE 95,485 0 0
CUTERA INC COM 232109108 9,660 257,600 SH SOLE 257,600 0 0
CVRX INC COM 126638105 6,365 1,059,040 SH SOLE 1,059,040 0 0
CVS HEALTH CORP COM 126650100 20,330 219,400 SH SOLE 219,400 0 0
DA32 LIFE SCNCE TEC ACQSTN C CLASS A COM 23312M106 485 50,000 SH SOLE 50,000 0 0
DEXCOM INC COM 252131107 3,520 47,236 SH SOLE 47,236 0 0
DICE THERAPEUTICS INC COM 23345J104 12,660 815,740 SH SOLE 815,740 0 0
EDAP TMS S A SPONSORED ADR 268311107 22,332 3,284,189 SH SOLE 3,284,189 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 5,330 846,000 SH SOLE 846,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 4,727 100,000 SH SOLE 100,000 0 0
ESSA PHARMA INC COM NEW 29668H708 13,132 4,168,799 SH SOLE 4,168,799 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108 4,263 78,400 SH SOLE 78,400 0 0
EVOLUS INC COM 30052C107 9,404 810,676 SH SOLE 810,676 0 0
EXACT SCIENCES CORP COM 30063P105 4,687 119,000 SH SOLE 119,000 0 0
FATE THERAPEUTICS INC COM 31189P102 4,817 194,400 SH SOLE 194,400 0 0
FIBROGEN INC COM 31572Q808 3,192 302,226 SH SOLE 302,226 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 6,209 77,842 SH SOLE 77,842 0 0
IMMUNIC INC COM 4525EP101 833 240,000 SH SOLE 240,000 0 0
INARI MED INC COM 45332Y109 4,916 72,298 SH SOLE 72,298 0 0
INCYTE CORP COM 45337C102 6,055 79,700 SH SOLE 79,700 0 0
INMODE LTD SHS M5425M103 4,201 187,449 SH SOLE 187,449 0 0
INSPIRE MED SYS INC COM 457730109 16,248 88,950 SH SOLE 88,950 0 0
IO BIOTECH INC COM 449778109 3,061 655,404 SH SOLE 655,404 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 7,944 719,600 SH SOLE 719,600 0 0
IRADIMED CORP COM 46266A109 21,069 620,765 SH SOLE 620,765 0 0
IVERIC BIO INC COM 46583P102 8,796 914,346 SH SOLE 914,346 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 2,084 252,000 SH SOLE 252,000 0 0
KRYSTAL BIOTECH INC COM 501147102 14,083 214,482 SH SOLE 214,482 0 0
LANTHEUS HLDGS INC COM 516544103 3,646 55,222 SH SOLE 55,222 0 0
LYRA THERAPEUTICS INC COM 55234L105 3,347 592,417 SH SOLE 592,417 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 3,815 196,018 SH SOLE 196,018 0 0
NATERA INC COM 632307104 4,674 131,873 SH SOLE 131,873 0 0
NEUROPACE INC COM 641288105 11,553 2,334,003 SH SOLE 2,334,003 0 0
NOVOCURE LTD ORD SHS G6674U108 923 13,275 SH SOLE 13,275 0 0
NURIX THERAPEUTICS INC COM 67080M103 12,600 994,492 SH SOLE 994,492 0 0
ORGANOGENESIS HLDGS INC COM 68621F102 25,796 5,286,167 SH SOLE 5,286,167 0 0
OUTSET MED INC COM 690145107 1,028 69,200 SH SOLE 69,200 0 0
PENUMBRA INC COM 70975L107 8,567 68,800 SH SOLE 68,800 0 0
PEPGEN INC COM 713317105 1,738 175,000 SH SOLE 175,000 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 7,732 4,134,868 SH SOLE 4,134,868 0 0
PLIANT THERAPEUTICS INC COM 729139105 3,925 490,000 SH SOLE 490,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 4,377 318,100 SH SOLE 318,100 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 5,326 75,094 SH SOLE 75,094 0 0
STERIS PLC SHS USD G8473T100 7,691 37,310 SH SOLE 37,310 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 7,464 258,100 SH SOLE 258,100 0 0
SURMODICS INC COM 868873100 24,609 661,004 SH SOLE 661,004 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 10,879 183,800 SH SOLE 183,800 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 16,718 1,300,000 SH Call SOLE 1,300,000 0 0
THE BEAUTY HEALTH COMPANY COM CL A 88331L108 42,130 3,276,037 SH SOLE 3,276,037 0 0
THERATECHNOLOGIES INC COM 88338H100 17,757 7,822,412 SH SOLE 7,822,412 0 0
TRANSMEDICS GROUP INC COM 89377M109 5,801 184,455 SH SOLE 184,455 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 69,641 295,541 SH SOLE 295,541 0 0
VAXCYTE INC COM 92243G108 8,065 370,650 SH SOLE 370,650 0 0
VERASTEM INC COM 92337C104 1,908 1,644,500 SH SOLE 1,644,500 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104 9,731 841,018 SH SOLE 841,018 0 0
VISTAGEN THERAPEUTICS INC COM NEW 92840H202 726 825,000 SH SOLE 825,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 2,282 75,000 SH SOLE 75,000 0 0
XILIO THERAPEUTICS INC COM 98422T100 1,325 453,660 SH SOLE 453,660 0 0
Y-MABS THERAPEUTICS INC COM 984241109 2,060 136,182 SH SOLE 136,182 0 0


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