Form 13F-HR Novo Holdings A/S For: Mar 31

May 17, 2021 7:03 AM EDT

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The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

Report for the Calendar Year or Quarter Ended: 03-31-2021
Check here if Amendment   Amendment Number:
This Amendment (Check only one.):   is a restatement.
  adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name: Novo Holdings A/S
Address: TUBORG HAVNEVEJ 19
HELLERUP , G72900
Form 13F File Number: 028-16231

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:
Name: Peter Haahr
Title: Chief Financial Officer
Phone: 45 3527 6500
Signature, Place, and Date of Signing:
/s/ Peter Haahr Hellerup , G7 05-17-2021
[Signature] [City, State] [Date]
Report Type (Check only one.):
X 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)
  13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)
  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)
Form 13F Summary Page
Report Summary:
Number of Other Included Managers: 0
Form 13F Information Table Entry Total: 51
Form 13F Information Table Value Total: 2,421,558
(thousands)
List of Other Managers Reporting for this Manager:
[If there are no entries in this list, omit this section.]
Form 13F File Number Name

List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]
No. Form 13F File Number Name

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACUTUS MED INC COM 005111109 3,409 255,000 SH SOLE 255,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 14,089 788,410 SH SOLE 788,410 0 0
AKOUOS INC COM 00973J101 6,370 459,290 SH SOLE 459,290 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 48,708 214,827 SH SOLE 214,827 0 0
ALIGOS THERAPEUTICS INC COM 01626L105 59,455 2,614,563 SH SOLE 2,614,563 0 0
AMICUS THERAPEUTICS INC COM 03152W109 19,393 1,962,880 SH SOLE 1,962,880 0 0
APPLE INC COM 037833100 126,719 1,037,404 SH SOLE 1,037,404 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 8,769 128,300 SH SOLE 128,300 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 19,154 197,000 SH SOLE 197,000 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104 148,226 4,503,991 SH SOLE 4,503,991 0 0
BROOKFIELD ASSET MGMT INC CL A LTD VT SH 112585104 136,658 3,070,957 SH SOLE 3,070,957 0 0
CABLE ONE INC COM 12685J105 86,556 47,341 SH SOLE 47,341 0 0
CHECKMATE PHARMACEUTICALS IN COM 162818108 26,345 2,170,100 SH SOLE 2,170,100 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 16,359 699,415 SH SOLE 699,415 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 4,147 271,378 SH SOLE 271,378 0 0
EARGO INC COM 270087109 36,817 737,071 SH SOLE 737,071 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105 181,584 5,587,207 SH SOLE 5,587,207 0 0
F-STAR THERAPEUTICS INC COM 30315R107 377 34,819 SH SOLE 34,819 0 0
FLEXION THERAPEUTICS INC COM 33938J106 12,560 1,403,370 SH SOLE 1,403,370 0 0
FREELINE THERAPEUTICS HLDGS SPONSORED ADS 35655L107 29,043 2,361,229 SH SOLE 2,361,229 0 0
GALECTO INC COM 36322Q107 15,162 2,497,791 SH SOLE 2,497,791 0 0
GALERA THERAPEUTICS INC COM 36338D108 21,689 2,459,021 SH SOLE 2,459,021 0 0
GRAYBUG VISION INC COM SHS 38942Q103 1,164 209,748 SH SOLE 209,748 0 0
GRITSTONE ONCOLOGY INC COM 39868T105 2,626 278,478 SH SOLE 278,478 0 0
HARMONY BIOSCIENCES HLDGS IN COM 413197104 110,234 3,336,378 SH SOLE 3,336,378 0 0
INARI MED INC COM 45332Y109 7,727 72,212 SH SOLE 72,212 0 0
INOGEN INC COM 45780L104 144,919 2,759,320 SH SOLE 2,759,320 0 0
INSMED INC COM PAR $.01 457669307 15,553 456,631 SH SOLE 456,631 0 0
INSPIRE MED SYS INC COM 457730109 8,280 40,000 SH SOLE 40,000 0 0
INTERSECT ENT INC COM 46071F103 10,626 508,922 SH SOLE 508,922 0 0
INOZYME PHARMA INC COM 45790W108 38,994 1,969,379 SH SOLE 1,969,379 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 14,621 461,811 SH SOLE 461,811 0 0
KINNATE BIOPHARMA INC COM 49705R105 9,348 300,000 SH SOLE 300,000 0 0
LAVA THERAPEUTICS NV SHS N51517105 50,542 3,327,312 SH SOLE 3,327,312 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 7,376 254,176 SH SOLE 254,176 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107 14,652 2,530,585 SH SOLE 2,530,585 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 48,463 2,445,147 SH SOLE 2,445,147 0 0
MORPHIC HLDG INC COM 61775R105 167,404 2,645,446 SH SOLE 2,645,446 0 0
NKARTA INC COM 65487U108 91,918 2,793,864 SH SOLE 2,793,864 0 0
PHARVARIS N V COM N69605108 1,399 50,000 SH SOLE 50,000 0 0
PRAXIS PRECISION MEDICINES I COM 74006W108 80,003 2,442,080 SH SOLE 2,442,080 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 22,474 867,724 SH SOLE 867,724 0 0
PULMONX CORP COM 745848101 8,556 187,047 SH SOLE 187,047 0 0
SEASPINE HLDGS CORP COM 81255T108 22,986 1,321,006 SH SOLE 1,321,006 0 0
SILK RD MED INC COM 82710M100 7,474 147,557 SH SOLE 147,557 0 0
SPERO THERAPEUTICS INC COM 84833T103 6,902 468,902 SH SOLE 468,902 0 0
SPRUCE BIOSCIENCES INC COM 85209E109 82,823 4,989,336 SH SOLE 4,989,336 0 0
VANGUARD INDEX FDS TOTAL STK MKT 922908769 399,718 1,933,900 SH SOLE 1,933,900 0 0
VAXCYTE INC COM 92243G108 8,235 416,937 SH SOLE 416,937 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106 7,009 838,360 SH SOLE 838,360 0 0
ZOGENIX INC COM NEW 98978L204 7,943 406,915 SH SOLE 406,915 0 0


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