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Form 13F-HR CLOUGH CAPITAL PARTNERS For: Mar 31

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May 16, 2022 12:17 PM EDT

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
Report for the Calendar Year or Quarter Ended: 03-31-2022
Check here if Amendment   Amendment Number:
This Amendment (Check only one.):   is a restatement.
  adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name: Clough Capital Partners L P
Address: 53 State Street
27th Floor
Boston , MA02109
Form 13F File Number: 028-10679

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:
Name: Daniel Gillis
Title: Chief Compliance Officer
Phone: 617-204-3409
Signature, Place, and Date of Signing:
/s/ Daniel Gillis Quincy , MA 05-16-2022
[Signature] [City, State] [Date]
Report Type (Check only one.):
X 13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)
  13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)
  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)
Form 13F Summary Page
Report Summary:
Number of Other Included Managers: 1
Form 13F Information Table Entry Total: 114
Form 13F Information Table Value Total: 1,317,893
(thousands)
List of Other Managers Reporting for this Manager:
[If there are no entries in this list, omit this section.]
Form 13F File Number Name
028-12502 Charles I. Clough, Jr.

List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]
No. Form 13F File Number Name
1 028-12502 Charles I. Clough, Jr.

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Expires: July 31, 2015
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBOTT LABS COM 002824100 5,445 46,000 SH DFND 1 46,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 10,768 164,320 SH DFND 1 164,320 0 0
ALIGN TECHNOLOGY INC COM 016255101 10,344 23,725 SH DFND 1 23,725 0 0
ALPHABET INC CAP STK CL C 02079K107 17,208 6,161 SH DFND 1 6,161 0 0
AMAZON COM INC COM 023135106 48,374 14,839 SH DFND 1 14,839 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 7,236 142,409 SH DFND 1 142,409 0 0
APPLE INC COM 037833100 29,832 170,850 SH DFND 1 170,850 0 0
ARCELLX INC COMMON STOCK 03940C100 16,619 1,209,876 SH DFND 1 1,209,876 0 0
ARVINAS INC COM 04335A105 15,432 229,300 SH DFND 1 229,300 0 0
BARINGS BDC INC COM 06759L103 4,589 443,826 SH DFND 1 443,826 0 0
BLACKROCK ENERGY & RES TR COM 09250U101 444 38,300 SH DFND 1 38,300 0 0
BLACKROCK INNOVATION AND GRW SHS BEN INT 09260Q108 2,330 204,582 SH DFND 1 204,582 0 0
BLACKROCK MUNIHLDS INVSTM QL COM 09254P108 567 46,233 SH DFND 1 46,233 0 0
BLACKSTONE SECD LENDING FD COMMON STOCK 09261X102 2,699 96,800 SH DFND 1 96,800 0 0
BLOCK INC CL A 852234103 26,807 197,690 SH DFND 1 197,690 0 0
BOEING CO COM 097023105 22,511 117,550 SH DFND 1 117,550 0 0
BOSTON SCIENTIFIC CORP COM 101137107 3,906 88,200 SH DFND 1 88,200 0 0
BRANDYWINEGBL GBL INCM OPP F COM 10537L104 1,878 185,580 SH DFND 1 185,580 0 0
C4 THERAPEUTICS INC COM STK 12529R107 8,641 356,181 SH DFND 1 356,181 0 0
CARNIVAL CORP COMMON STOCK 143658300 25,517 1,261,970 SH DFND 1 1,261,970 0 0
CBRE GBL REAL ESTATE INC FD COM 12504G100 267 29,500 SH DFND 1 29,500 0 0
CENTER COAST BRKFLD MLP ENRG SHS BEN INT 151461209 2,116 121,447 SH DFND 1 121,447 0 0
CHECKMATE PHARMACEUTICALS IN COM 162818108 3,629 1,137,764 SH DFND 1 1,137,764 0 0
CHENIERE ENERGY INC COM NEW 16411R208 20,118 145,100 SH DFND 1 145,100 0 0
CISCO SYS INC COM 17275R102 3,552 63,700 SH DFND 1 63,700 0 0
CLEARBRIDGE ENERGY MIDSTRM O COM 18469P209 437 15,500 SH DFND 1 15,500 0 0
CLEARBRIDGE MLP AND MIDSTRM COM 184692200 432 12,800 SH DFND 1 12,800 0 0
CLEARBRIDGE MLP AND MIDSTRM COM 18469Q207 429 14,700 SH DFND 1 14,700 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 16,264 1,370,159 SH DFND 1 1,370,159 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 12,937 206,107 SH DFND 1 206,107 0 0
CUSHING MLP & INFRASTRUCT COM NEW 231631300 1,294 37,100 SH DFND 1 37,100 0 0
D R HORTON INC COM 23331A109 18,054 242,300 SH DFND 1 242,300 0 0
DELAWARE INVTS NATL MUN INCO SH BEN INT 24610T108 1,825 144,247 SH DFND 1 144,247 0 0
DELAWARE IVY HIGH INCOME OPP COM 246107106 471 37,200 SH DFND 1 37,200 0 0
DEXCOM INC COM 252131107 2,098 4,100 SH DFND 1 4,100 0 0
DOXIMITY INC CL A 26622P107 11,674 224,110 SH DFND 1 224,110 0 0
EATON VANCE TAX ADVT DIV INC COM 27828G107 275 9,500 SH DFND 1 9,500 0 0
EATON VANCE TX ADV GLBL DIV COM 27828S101 202 9,806 SH DFND 1 9,806 0 0
EQUITABLE HLDGS INC COM 29452E101 25,898 837,840 SH DFND 1 837,840 0 0
EXXON MOBIL CORP COM 30231G102 28,948 350,500 SH DFND 1 350,500 0 0
FIRST AMERN FINL CORP COM 31847R102 46,985 724,846 SH DFND 1 724,846 0 0
FRANKLIN LTD DURATION INCOME COM 35472T101 3,435 453,195 SH DFND 1 453,195 0 0
GABELLI UTIL TR RIGHT 04/19/2022 36240A176 46 234,709 SH DFND 1 234,709 0 0
GODADDY INC CL A 380237107 18,657 222,900 SH DFND 1 222,900 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 2,850 3,500,000 PRN DFND 1 3,500,000 0 0
GUGGENHEIM STRATEGIC OPPORTU COM SBI 40167F101 1,531 80,512 SH DFND 1 80,512 0 0
HCA HEALTHCARE INC COM 40412C101 7,874 31,420 SH DFND 1 31,420 0 0
HERTZ GLOBAL HLDGS INC COM NEW 42806J700 4,441 200,500 SH DFND 1 200,500 0 0
HERTZ GLOBAL HLDGS INC W EXP 06/30/205 42806J148 12,179 793,400 SH DFND 1 793,400 0 0
HERZFELD CARIBBEAN BASIN FD COM 42804T106 182 34,212 SH DFND 1 34,212 0 0
HIGHLAND GLOBAL ALLOCATION F COM 43010T104 1,142 115,908 SH DFND 1 115,908 0 0
HOLOGIC INC COM 436440101 13,384 174,220 SH DFND 1 174,220 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 8,329 27,610 SH DFND 1 27,610 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 7,251 20,000 SH Put DFND 1 20,000 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 4,204 26,695 SH DFND 1 26,695 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 10,338 66,410 SH DFND 1 66,410 0 0
JOHNSON & JOHNSON COM 478160104 19,726 111,300 SH DFND 1 111,300 0 0
KINDER MORGAN INC DEL COM 49456B101 30,311 1,602,892 SH DFND 1 1,602,892 0 0
KYMERA THERAPEUTICS INC COM 501575104 7,859 185,700 SH DFND 1 185,700 0 0
LAM RESEARCH CORP COM 512807108 15,982 29,728 SH DFND 1 29,728 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 4,713 129,691 SH DFND 1 129,691 0 0
LENNAR CORP CL A 526057104 13,925 171,549 SH DFND 1 171,549 0 0
LILLY ELI & CO COM 532457108 3,440 12,013 SH DFND 1 12,013 0 0
LOCKHEED MARTIN CORP COM 539830109 10,382 23,520 SH DFND 1 23,520 0 0
LUMENTUM HLDGS INC COM 55024U109 8,755 89,700 SH DFND 1 89,700 0 0
LYFT INC CL A COM 55087P104 3,206 83,500 SH DFND 1 83,500 0 0
MCKESSON CORP COM 58155Q103 3,438 11,232 SH DFND 1 11,232 0 0
MERCK & CO INC COM 58933Y105 18,076 220,300 SH DFND 1 220,300 0 0
MICRON TECHNOLOGY INC COM 595112103 14,965 192,124 SH DFND 1 192,124 0 0
MICROSOFT CORP COM 594918104 69,788 226,357 SH DFND 1 226,357 0 0
MILLER HOWARD HIGH INC EQTY COM SHS BEN IN 600379101 4,538 406,604 SH DFND 1 406,604 0 0
MIRATI THERAPEUTICS INC COM 60468T105 4,350 52,902 SH DFND 1 52,902 0 0
NORTHROP GRUMMAN CORP COM 666807102 21,028 47,020 SH DFND 1 47,020 0 0
NUVEEN CORE EQUITY ALPHA FD COM 67090X107 1,782 101,601 SH DFND 1 101,601 0 0
NVIDIA CORPORATION COM 67066G104 31,753 116,370 SH DFND 1 116,370 0 0
PALO ALTO NETWORKS INC COM 697435105 27,225 43,735 SH DFND 1 43,735 0 0
PARAMOUNT GLOBAL CLASS B COM 92556H206 17,805 470,900 SH DFND 1 470,900 0 0
PFIZER INC COM 717081103 24,177 467,000 SH DFND 1 467,000 0 0
PIMCO GLOBAL STOCKSPLS INCM COM 722011103 726 76,200 SH DFND 1 76,200 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 45,324 457,490 SH DFND 1 457,490 0 0
REDWOOD TR INC COM 758075402 15,705 1,491,500 SH DFND 1 1,491,500 0 0
REDWOOD TRUST INC NOTE 4.750% 8/1 758075AC9 1,998 1,978,000 PRN DFND 1 1,978,000 0 0
RIVERNORTH FLEXIBLE MUNI INC COM 76883Y107 372 22,689 SH DFND 1 22,689 0 0
ROYAL CARIBBEAN GROUP COM V7780T103 27,400 327,047 SH DFND 1 327,047 0 0
SABA CAPITAL INCOME & OPRNT SHARES 78518H103 4,069 900,130 SH DFND 1 900,130 0 0
SALIENT MIDSTREAM & MLP FD SH BEN INT 79471V105 1,095 132,832 SH DFND 1 132,832 0 0
SERVICENOW INC COM 81762P102 8,860 15,910 SH DFND 1 15,910 0 0
SPDR SER TR AEROSPACE DEF 78464A631 20,302 162,830 SH DFND 1 162,830 0 0
SPECIAL OPPORTUNITIES FD INC COM 84741T104 845 56,300 SH DFND 1 56,300 0 0
STARWOOD PPTY TR INC COM 85571B105 49,660 2,054,600 SH DFND 1 2,054,600 0 0
STARWOOD PPTY TR INC NOTE 4.375% 4/0 85571BAH8 11,092 10,815,000 PRN DFND 1 10,815,000 0 0
STRYKER CORPORATION COM 863667101 6,684 25,000 SH DFND 1 25,000 0 0
SURGERY PARTNERS INC COM 86881A100 16,448 298,781 SH DFND 1 298,781 0 0
TELADOC HEALTH INC NOTE 1.250% 6/0 87918AAF2 1,271 1,500,000 PRN DFND 1 1,500,000 0 0
TENET HEALTHCARE CORP COM NEW 88033G407 11,905 138,500 SH DFND 1 138,500 0 0
TESLA INC COM 88160R101 24,237 22,492 SH DFND 1 22,492 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 5,414 9,167 SH DFND 1 9,167 0 0
TORTOISE ENERGY INDEPENDENC COM 89148K200 481 16,205 SH DFND 1 16,205 0 0
TORTOISE ENERGY INFRA CORP COM 89147L886 508 14,700 SH DFND 1 14,700 0 0
TORTOISE MIDSTRM ENERGY FD I COM 89148B200 2,960 77,968 SH DFND 1 77,968 0 0
TORTOISE PIPELINE & ENERGY F COM 89148H207 365 12,441 SH DFND 1 12,441 0 0
TORTOISE PWR & ENERGY INFRAS COM 89147X104 399 28,021 SH DFND 1 28,021 0 0
TRANSDIGM GROUP INC COM 893641100 18,773 28,814 SH DFND 1 28,814 0 0
UNITEDHEALTH GROUP INC COM 91324P102 20,078 39,370 SH DFND 1 39,370 0 0
VANECK ETF TRUST PHARMACEUTCL ETF 92189F692 2,768 34,700 SH DFND 1 34,700 0 0
VANECK ETF TRUST OIL SERVICES ETF 92189H607 27,269 96,510 SH DFND 1 96,510 0 0
VERACYTE INC COM 92337F107 4,071 147,670 SH DFND 1 147,670 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 15,175 58,150 SH DFND 1 58,150 0 0
VISA INC COM CL A 92826C839 30,751 138,660 SH DFND 1 138,660 0 0
WALKER & DUNLOP INC COM 93148P102 8,414 65,010 SH DFND 1 65,010 0 0
WESTERN ASSET EMERGING MKTS COM 95766A101 450 41,900 SH DFND 1 41,900 0 0
WESTERN AST INFL LKD OPP & I COM 95766R104 766 63,800 SH DFND 1 63,800 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 12,033 94,080 SH DFND 1 94,080 0 0
ZOETIS INC CL A 98978V103 7,106 37,681 SH DFND 1 37,681 0 0

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