| Cash flows from operating activities | |
| Net income (loss) | |
| Adjustments to reconcile net income (loss) to net cash used in operating activities: | |
| Depreciation and amortization | 386K |
| Amortization of discount/premium on investments | 6K |
| Stock-based compensation expense | 3.35M |
| Gain on disposal of property and equipment | 0 |
| Changes in operating assets and liabilities: | |
| Receivable from Takeda | 17.49M |
| Income taxes receivable | |
| Prepaid expenses and other current assets | -228K |
| Other assets | |
| Accounts payable | 2.72M |
| Accrued liabilities | -9.34M |
| Accrued clinical trial expenses | -610K |
| Payable to Takeda | |
| Deferred revenue | |
| Long-term income tax liability | |
| Other long-term liabilities | |
| Net cash used in operating activities | |
| Cash flows from investing activities | |
| Purchases of property and equipment | 0 |
| Purchases of investments | |
| Proceeds from sales of investments | |
| Proceeds from maturities of investments | 3.6M |
| Proceeds from sale of property and equipment | 0 |
| Net cash provided by (used in) investing activities | |
| Cash flows from financing activities | |
| Proceeds from issuance of common stock upon exercise of stock options | 271K |
| Proceeds from issuance of common stock under employee stock purchase plan | |
| Proceeds from common stock issued upon public offering, net of issuance cost | |
| Repayment of UBS loan | |
| Net cash provided by (used in) financing activities | |
| Net increase (decrease) in cash and cash equivalents | |
| Cash and cash equivalents at beginning of the period | 68.27M |
| Cash and cash equivalents at end of the period | 46.62M |