GlaxoSmithKline (GSK) Announces Positive Data from 7-Year Benlysta Study in SLE Patients
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GlaxoSmithKline (GSK) Announces Results from Two Sirukumab Phase 3 in RA; SIRROUND-T Study Met Primary Endpoint
November 16, 2016 11:20 AM ESTGlaxoSmithKline (NYSE: GSK) announced results from two pivotal phase III studies evaluating subcutaneous sirukumab, a human anti-interleukin (IL)-6 monoclonal antibody in development for the treatment of adults with moderately to severely active rheumatoid arthritis (RA).
The first study (SIRROUND-T), in patients who were refractory to or intolerant to one or more anti-tumor necrosis factor (TNF) agents, demonstrated that sirukumab met the primary endpoint showing significant improvement in the signs and symptoms of moderately to severely active RA compared to placebo. The second study (SIRROUND-H), a head-to-head study in patients who were refractory to or... More