bluebird bio (BLUE) ASH Abstract Data Fairly Consistent With Previously Published Data - Leerink
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bluebird bio to Present New Data from Three LentiGlobinTM Clinical Studies at American Society of Hematology (ASH) Annual Meeting
November 3, 2016 9:01 AM EDTData from the Northstar (HGB-204) study of LentiGlobin drug product in transfusion-dependent -thalassemia (TDT) show that all five patients with non-0/0 genotypes and 12 months of follow-up remained free of transfusions, and patients with 0/0 genotypes and 12 months of follow-up (n=5) had a median reduction in transfusion volume of 60%
The median HbAT87Q level at six months in Northstar was 4.7 g/dl across all genotypes, and levels were generally sustained over the second year of follow-up
All patients with TDT from the HGB-205 study remained free of transfusions,... More