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OncoGenex Pharma (OGXI) Announces Strong Survival Data from Apatorsen Phase 2 in MBC

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OncoGenex Announces Positive Survival Results from Apatorsen Phase 2 Borealis-2™ Trial in Metastatic Bladder Cancer

October 25, 2016 5:00 PM EDT

Randomized Trial of 200 Patients Meets Primary Endpoint of Overall Survival

BOTHELL, Wash. and VANCOUVER, British Columbia, Oct. 25, 2016 /PRNewswire/ -- OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) announced today positive survival results from the final analysis of the Phase 2 Borealis-2 trial of apatorsen in combination with docetaxel treatment that enrolled 200 patients with metastatic bladder cancer whose disease had progressed following first-line platinum-based chemotherapy. Patients who received apatorsen treatment experienced a 20% reduction in risk of death, compared to patients receiving docetaxel alone (HR=.80; 95% CI: 0.65-0.98; p=0.078). The primary analysis was a superiority test of... More