Maxim Keeps ContraVir Pharma (CTRV) at 'Buy' as CMX157 Progresses into Phase 2a for HBV
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ContraVir Pharma (CTRV) Climbs to Session High, Shares Up 17%
October 17, 2016 10:20 AM EDTContraVir Pharma (NASDAQ: CTRV) Climbs to Session High, Shares Up 17%
... MoreContraVir Pharma (CTRV) Begins Enrollment in CMX157 Phase 2a Dose-Escalation Study
October 17, 2016 6:37 AM EDTContraVir Pharmaceuticals, Inc. (Nasdaq: CTRV) announced that following a positive recommendation from an independent Data Safety Monitoring Board (DSMB), the company has begun enrolling the next dosing group in its head-to-head Phase 2a dose-escalation study comparing the safety and efficacy of ContraVir's CMX157 to tenofovir disoproxil fumarate (TDF, marketed by Gilead Sciences as Viread®) in patients with chronic hepatitis B (HBV). ContraVir expects to complete the remaining two escalation cohorts and report top-line results by year-end 2016.
The DSMB conducted an independent review of the safety, tolerability and pharmacokinetic profile of CMX157 from... More
Maxim Positive on ContraVir Pharma (CTRV) Following CMX157 Phase 2a Update
October 13, 2016 7:30 AM EDTMaxim affirms ContraVir Pharmaceuticals (Nasdaq: CTRV) at Buy with a price target of $4 after the company reported positive interim data for CMX157, the Company's highly potent prodrug of tenofovir, from its ongoing Phase 2a multiple ascending dose clinical study.
Maxim noted:
More... MoreContraVir Pharma (CTRV) Says CMX157 Demonstrates Significant Viral Load Reduction in Phase 2a Study in Hepatitis B
October 13, 2016 6:39 AM EDTContraVir Pharmaceuticals, Inc. (NASDAQ: CTRV), a biopharmaceutical company focused on the development and commercialization of targeted antiviral therapies, today reported positive interim data for CMX157, the Company's highly potent prodrug of tenofovir, from its ongoing Phase 2a multiple ascending dose clinical study. The head-to-head study is the first evaluation of CMX157 in HBV patients, and directly compares CMX157 to tenofovir disoproxil fumarate (TDF, Gilead's Viread®) in chronically infected hepatitis B (HBV) patients.
Patients successfully completed both 5 mg and 10 mg cohorts, and interim data reported below are from 10 HBV-infected patients who completed 14... More