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Pfizer (PFE) Announces Strong Data from SUTENT Phase 3 in RCC; DFS Extension Noted

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First Positive Phase 3 Results in Adjuvant Setting for Renal Cell Carcinoma Show SUTENT® (sunitinib) Extended Disease Free Survival After Surgical Removal

October 10, 2016 2:15 AM EDT

Late-breaking data to be presented at the ESMO 2016 Congress and Published in The New England Journal of Medicine

NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) today announced results from the Phase 3 S-TRAC clinical trial (Sunitinib Trial as Adjuvant Treatment of Renal Cancer) investigating SUTENT® (sunitinib) as adjuvant therapy. The trial showed SUTENT extended disease-free survival (DFS) by more than one year versus placebo in patients who were at high risk for recurrence after surgical resection of renal cell carcinoma (RCC) (HR 0.761; P=0.030 [95% CI: 0.594-0.975]). These results will be... More

Pfizer Presents Promising New Immunotherapy Combination Data With INLYTA® (axitinib) In Advanced Renal Cell Carcinoma (RCC)

October 9, 2016 10:30 AM EDT

Data From a Trial of INLYTA With Pembrolizumab Provides Additional Support for Novel Immunotherapy Combinations in RCC

Preliminary Results from an Ongoing Trial of INLYTA with Avelumab in RCC Were Also Presented

NEW YORK--(BUSINESS WIRE)-- Pfizer Inc. (NYSE: PFE) today announced data from an ongoing, investigational Phase 1b study of INLYTA® (axitinib) combined with the checkpoint inhibitor pembrolizumab (A4061079, NCT02133742), a PD-1 inhibitor known as KEYTRUDA® and marketed by Merck, known as MSD outside the United States and Canada, in treatment-naïve... More