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Intra-Cellular Therapies (ITCI) Sinks 69% as Trading Resumes

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Intra-Cellular Therapies (ITCI) PT Cut to $22 at Piper Jaffray; Thinks Trial Not Drug a Failure

September 29, 2016 6:47 AM EDT

Piper Jaffray analyst Charles Duncan slashed his price target on Intra-Cellular Therapies (NASDAQ: ITCI) to $22.00 (from $57.00) after the company announced that its second P3 in schizophrenia failed to meet the primary endpoint, with 007 generating improvements in the PANSS that were over-shadowed by a higher-than-expected placebo response. The analyst maintained... More

Intra-Cellular Therapies (ITCI) PT Cut to $29 at Leerink Partners Amid ITI-007 Failure

September 29, 2016 6:38 AM EDT

Leerink Partners analyst Seamus Fernandez slashed his price target on Intra-Cellular Therapies (NASDAQ: ITCI) to $29.00 (from $95.00) but maintained an Outperform rating on the disappointing result that ITCI's leading drug candidate, ITI-007, failed to separate from placebo in the second Ph 3 schizophrenia study. Neither the 60... More

Intra-Cellular Therapies (ITCI) to Resume Trading at 4:30 PM ET

September 28, 2016 4:10 PM EDT

Intra-Cellular Therapies (NASDAQ: ITCI) to Resume Trading at 4:30 PM ET

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Intra-Cellular Therapies (ITCI) Announces ITI-007 Phase 3 Missed Primary Endpoint in Schizophrenia

September 28, 2016 4:03 PM EDT

Intra-Cellular Therapies, Inc. (Nasdaq: ITCI) announced top-line results from the second Phase 3 clinical trial (Study 302) of ITI-007, an oral, first-in-class investigational medicine for the treatment of schizophrenia. In this trial, neither dose of ITI-007 separated from placebo on the primary endpoint, change from baseline on the Positive and Negative Syndrome Scale (PANSS) total score, in the pre-defined patient population. The active control, risperidone, did separate from placebo. In this trial, ITI-007 was statistically significantly better than risperidone on key safety and tolerability parameters and exhibited a safety profile similar to placebo. This replicates the... More