Merck (MRK) to Discontinue Development of Odanacatib for Osteoporosis
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Merck Provides Update on Odanacatib Development Program
September 2, 2016 7:00 AM EDTKENILWORTH, N.J.--(BUSINESS WIRE)-- Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that it is discontinuing the development of odanacatib, Mercks investigational cathepsin K inhibitor for osteoporosis, and will not seek regulatory approval for its use. Merck previously reported a numeric imbalance in adjudicated stroke events in the pivotal Phase 3 fracture outcomes study in postmenopausal women. The company has decided to discontinue development after an independent adjudication and analysis of major adverse cardiovascular events confirmed an increased risk of stroke. The data from the... More
