AVEO Oncology (AVEO) Commences Tivozanib + Opdivo Clinical Trial in Advanced RCC
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AVEO Initiates the Evaluation of Tivozanib in Combination with Bristol-Myers Squibb’s Opdivo® (nivolumab) in Advanced Renal Cell Carcinoma
August 15, 2016 7:00 AM EDT-Phase 1/2 TiNivo Trial to Commence at the Institut Gustave Roussy in Paris-
CAMBRIDGE, Mass.--(BUSINESS WIRE)-- AVEO Oncology (NASDAQ: AVEO) today announced the initiation of a clinical evaluation of AVEOs oral, once-daily, vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor (TKI), tivozanib, in combination with Bristol-Myers Squibbs anti-PD-1 therapy, Opdivo® (nivolumab), in advanced renal cell carcinoma (RCC). Bristol-Myers Squibb will supply nivolumab for use in the Phase 1/2 AVEO-sponsored TiNivo trial. The trial will be led by the Institut Gustave Roussy in Paris under the direction of Professor Bernard Escudier, MD,... More