StampKey - The Easiest Way to Carry Your Loyalty Cards with You on Your Smartphone Oct 24, 2014 06:18AM

SAN JOSE, Costa Rica, Oct. 24, 2014 /PRNewswire/ -- Who hasn't experienced the numerous restaurant, store, supermarket, gym or gas station loyalty cards one carries in the wallet, purse or keychain? Plastic cards weigh heavy on your purse, can create frustrations if one forgets them at home, so the updated StampKey app might be a smart solution for you!

StampKey offers the simplest way to store loyalty cards, barcodes, QR codes or customer numbers in a smartphone. StampKey takes a digital image of each card, which after a quick edit will be stored in its digital card organizer, where it can be retrieved quickly and zoomed to full screen whenever needed. So you can finally carry nearly all your loyalty cards in one app - instead of plastic cards - with you in your smartphone.

Included in the app is a professional digital loyalty stamp solution for businesses developed for restaurants, bars, gyms, service stations and others. The StampKey app comes with a in built QR-code for each user, which allows businesses to scan the QR codes of other StampKey users as displayed on their smartphones or via a printed business card (available on StampKey website). The scanning can occur during 12 hours without any internet connection making it an attractive alternative for some places.

StampKey app is available for download for free from iTunes or Google Play. StampKey has just been updated to it's most complete version yet incorporating English, Spanish and German language editions, an image editor, the ability to import and export loyalty card images, using the app without a login, faster stamping, performance enhancements and in-built promotion functionalities for business users. While StampKey is free to download for personal use, businesses require a subscription (free trial subscription available) to use all of the extra capabilities offered.

Download StampKey today and simplify your loyalty card collection starting as of today!

This press release was issued through 24-7PressRelease.com. For further information, visit http://www.24-7pressrelease.com.

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/stampkey---the-easiest-way-to-carry-your-loyalty-cards-with-you-on-your-smartphone-507871940.html

SOURCE StampKey


Dining Innovation Group Opens First Japanese-Style BBQ Restaurant KINTAN in London Oct 24, 2014 06:16AM

Developed by Mr. Nishiyama, Founder of Japan's Number One Grill Restaurant Chain

LONDON--(BUSINESS WIRE)-- DINING INNOVATION GROUP, known for developing Japanese restaurants in various locations globally, has opened a KINTAN in the Holborn area of London. KINTAN is a 'yakiniku' restaurant (or Japanese-style BBQ) that has gained popularity not only in Japan, but in locations throughout the world as well. Numerous visitors have already been savoring its authentic yakiniku menu since opening in August.

DINING INNOVATION GROUP, known for developing Japanese restaurants in various locations globally, has opened a KINTAN in the Holborn area of London. KINTAN is a 'yakiniku' restaurant (or Japanese-style BBQ) that has gained popularity not only in Japan, but in locations throughout the world as well. (Photo: Business Wire)

KINTAN was born from the desire to provide Europe with authentic Japanese-style yakiniku that uses carefully selected ingredients. The innovative restaurant was developed by Tomoyoshi Nishiyama, the talent behind creating Japan's number one yakiniku restaurant chain. Thirty restaurants are already in operation in the US and have garnered significant popularity. The popular US menu's full line-up has been adopted at the London location. Prices have also been set quite reasonably - lunch can be enjoyed from 9 pounds, and dinner ensembles from 29.5 pounds.

"Yakiniku" refers to Japanese-style BBQs. This new dining style allows people to cook meat, seafood, and vegetables themselves right at the table to their desired doneness. The restaurant features state-of-the-art smokeless roasters that keep the atmosphere smoke and odor free. KINTAN provides authentic Japanese yakiniku in an atmosphere that embodies the Japanese cultural concept of harmony.

KINTAN Overview

Address: 34-36 High Holborn London WC1V 6AEPhone: 020-3150-2501 / 07477-692466 (for Japanese speakers)Hours of operation:

Weekdays 12:00-15:00, 17:30-23:00Saturday 12:00-23:00Sunday 12:00-22:00

Website: http://kintan.uk/Facebook: https://www.facebook.com/pages/Kintan-Japanese-BBQ/755670741146306

About DINING INNOVATION GROUP

With a mission of promoting "Japanese food culture to the world," DINING INNOVATION GROUP is engaged in business related to Japanese foods such as yakiniku, yakitori, ramen, udon, soba, and more. In addition to Japan, the group operates restaurants in Europe, China, Hong Kong, and ASEAN member countries, and has expanded to 70 locations.

DINING INNOVATION UK LTD.

Akihisa Nagae, 020-3150-2501 / 07477-692466 (for Japanese speakers)

nagae@dining-innovation.com

Source: DINING INNOVATION GROUP


Verastem Presents New Data on Mesothelioma Programs at the 12th International Mesothelioma Interest Group Meeting Oct 24, 2014 06:06AM

-Results from a Window of Opportunity study in surgically-eligible patients demonstrate a reduction in pFAK, cancer stem cell markers and tumor size following 12 days of treatment with VS-6063-

BOSTON--(BUSINESS WIRE)-- Verastem, Inc. (NASDAQ: VSTM), focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the presentation of clinical and preclinical data in oral presentation and discussion sessions at the 12th International Mesothelioma Interest Group (iMig) Conference being held October 22-24, 2014, at the Cape Town International Conference Centre in Cape Town, South Africa.

Professor Raphael Bueno, M.D., Chief of Thoracic Surgery, Brigham and Women’s Hospital (BWH), Boston and Principal Investigator of Verastem’s ongoing Window of Opportunity study presented preliminary clinical results in an oral presentation. The study is evaluating the biomarker response to VS-6063 (defactinib), an oral small molecule that targets cancer stem cells through the inhibition of focal adhesion kinase (FAK) in patients with resectable pleural mesothelioma. Biopsies of the tumor are taken before and after oral administration of VS-6063 (400mg BID) for 12 days. The study also measures tumor size using CT/PET scans before and after the 12-day administration of VS-6063. All study patients were enrolled at the BWH clinical site.

An analysis of the preliminary data (n=10) showed that VS-6063 reduced FAK activity (pFAK-Y397) by an average of 70% in the patients evaluated to date, and reduced the presence of cancer stem cell markers in the post-treatment biopsies in 5 out of the 7 patients with evaluable paired biopsies. Measurement of tumor size by CT/PET using RECIST modified for mesothelioma confirmed that there was no progression of disease while on the 12 day treatment with single agent VS-6063 in any of the 10 patients. Moreover, in 2 patients, tumor shrinkage consistent with a partial response (-30%, -49%) was noted. VS-6063 was well tolerated with no apparent negative impact on surgical outcome.

“These initial biopsy data show signs of activity against biomarkers of cancer stem cells as well as intriguing reductions in tumor size, after short-term exposure to single agent VS-6063,” said Dr. Bueno. “To follow up on these encouraging results, the protocol is being amended to explore more extended dosing in 10-15 additional patients with mesothelioma prior to surgery. The window of opportunity before elective surgery provides a novel platform for the clinical evaluation of promising new agents for the treatment of this devastating disease.”

“This study was designed to evaluate potential biomarkers of response to VS-6063 treatment in patients with pleural mesothelioma,” said Dr. Joanna Horobin, Verastem Chief Medical Officer. “We are encouraged by the biomarker response, and intrigued by the tumor shrinkage observed after 12 days of VS-6063 administration. As we expand our clinical program with VS-6063 in mesothelioma into other patient settings, we are encouraged by these interesting signs of clinical activity.”

In addition to the Window of Opportunity study, Verastem is conducting the registration-directed COMMAND study as a maintenance treatment immediately following successful front-line therapy with Alimta and cisplatin in patients with malignant pleural mesothelioma. Verastem anticipates starting a study of VS-6063 and VS-5584 in combination for patients with relapsed or progressive malignant pleural mesothelioma in early 2015.

Verastem also presented preclinical data at the conference demonstrating the ability of VS-6063 and the combination of VS-6063 and VS-5584 to target and kill cancer stem cells in models of mesothelioma. In addition, Professor Robert Weinberg, Ph.D., Whitehead Institute/Massachusetts Institute of Technology, Verastem co-founder and Chair of the Scientific Advisory Board, gave a keynote address to open the symposium entitled: “Cancer Stem Cells as Target Pathways.” These presentations support the ongoing and planned clinical trials that Verastem is conducting in patients with mesothelioma.

A summary of the data presented by Verastem at the conference is below:

Oral Presentations and Discussions

iMig Special Keynote Lecture: “Cancer Stem Cells as Target Pathways”Presenter: Robert Weinberg, Ph.D., Whitehead Institute/Massachusetts Institute of Technology, Verastem scientific cofounder and chair of the Scientific Advisory BoardDate and time: Wednesday, October 22, 2014, 8:50 AM (local time)Link to presentation: http://bit.ly/12otlcV

Presentation Title: “FAK Inhibitor VS-6063 (defactinib) Targets Mesothelioma Cancer Stem Cells which are Enriched by Standard of Care Chemotherapy”Presenter: Paul Baas, M.D., Ph.D., Department of Thoracic Oncology, The Netherlands Cancer InstituteDate and time: Thursday, October 23, 2014, 3:30 PM (local time)Link to presentation: http://bit.ly/12otlcV

Presentation Title: “Determination of Biomarker Response in a Phase II Window of Opportunity Study of Defactinib (VS-6063), a Focal Adhesion Kinase (FAK) Inhibitor, in Subjects with Resectable MPM”Presenter: Raphael Bueno, M.D., Chief, Division of Thoracic Surgery, Brigham & Women’s HospitalDate and time: Thursday, October 23, 2014, 3:45 PM (local time)Link to presentation: http://bit.ly/12otlcV

Presentation Title: “The Cancer Stem Cell Inhibitors VS-6063 (defactinib) and VS-5584 Exhibit Synergistic Anticancer Activity in Preclinical Models of Mesothelioma”Presenter: Mitchell Keegan, Ph.D., Vice President, Development, VerastemDate and time: Friday, October 24, 2014, 10:30 AM (local time)Link to presentation: http://bit.ly/12otlcV

Poster Presentation

Presentation Title: COMMAND: A Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Defactinib as Maintenance Therapy in Subjects with Malignant Pleural Mesothelioma which has not Progressed on at Least 4 cycles of Pemetrexed/Platinum Therapy”Presenter: Mitchell Keegan, Ph.D., Vice President, Development, VerastemDate and time: Thursday, October 23, 2014, 10:30AM (local time)Link to poster: http://bit.ly/12otlcV

Several of the above-mentioned studies were selected to be featured in the “Best of iMig” series, which highlighted the most relevant studies from the conference. Video of the presentations can be found at http://bit.ly/12d3OU1

About Malignant Pleural Mesothelioma

Malignant pleural mesothelioma is an aggressive form of cancer that occurs in the mesothelium, the thin layer of tissue that covers the lungs. Mesothelioma is associated with exposure to asbestos in most cases. According to the World Health Organization, there are a total of 59,000 cases of mesothelioma worldwide each year. Most mesotheliomas begin as one or more nodules that progressively grow to form a solid coating of tumor surrounding the lung leading to eventual suffocation and death. A high percentage of mesotheliomas contain cancer stem cells which are generally resistant to the currently available treatment options for mesothelioma.

About VS-6063

VS-6063 (defactinib) is an orally available compound designed to target cancer stem cells through the potent inhibition of focal adhesion kinase (FAK). Cancer stem cells are an underlying cause of tumor resistance to chemotherapy, recurrence and ultimate disease progression. Research by Robert Weinberg, Ph.D., scientific cofounder and chair of Verastem’s Scientific Advisory Board, and Verastem has demonstrated that FAK activity is critical for the growth and survival of cancer stem cells. VS-6063 is currently being studied in the registration-directed COMMAND trial in mesothelioma (www.COMMANDmeso.com), a “Window of Opportunity” study in patients with mesothelioma prior to surgery, a Phase 1/1b study in combination with paclitaxel in patients with ovarian cancer, and a trial in patients with Kras-mutated non-small cell lung cancer. VS-6063 has been granted orphan drug designation in the U.S. and EU for use in mesothelioma.

About VS-5584

VS-5584 is an orally available compound that has demonstrated potent and highly selective activity against class 1 PI3K enzymes and dual inhibitory actions against mTORC1 and mTORC2. In preclinical studies, VS-5584 has been shown to reduce the percentage of cancer stem cells and induce tumor regression in chemotherapy-resistant models. Verastem is currently conducting a Phase 1 dose escalation trial of VS-5584 in patients with advanced solid tumors and lymphomas.

About Verastem, Inc.

Verastem, Inc. (NASDAQ: VSTM) is discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells. Cancer stem cells are an underlying cause of tumor recurrence and metastasis. Verastem is developing small molecule inhibitors of signaling pathways that are critical to cancer stem cell survival and proliferation: FAK, PI3K/mTOR and Wnt. For more information, please visit www.verastem.com.

Forward-looking statements:

This press release includes forward-looking statements about the Company’s strategy, future plans and prospects, including statements regarding the development of the Company’s compounds, including VS-6063, or defactinib, andVS-5584 and the Company’s FAK inhibition program and PI3K/mTOR program generally, the timeline for clinical development and regulatory approval of the Company’s compounds, the expected timing for the reporting of data from ongoing trials, and the structure of the Company’s planned or pending clinical trials. The words “anticipate,” “appear,” “believe,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “target,” “potential,” “will,” “would,” “could,” “should,” “continue,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Each forward-looking statement is subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied in such statement. Applicable risks and uncertainties include the risks that the preclinical testing of the Company’s compounds and preliminary or interim data from clinical trials, including the Window of Opportunity study, may not be predictive of the results or success of ongoing or later clinical trials, that data may not be available when we expect it to be, that enrollment of clinical trials may take longer than expected, that the Company will be unable to successfully complete the clinical development of its compounds, including VS-6063 and VS-5584, that the development of the Company’s compounds will take longer or cost more than planned, and that the Company’s compounds will not receive regulatory approval or become commercially successful products. Other risks and uncertainties include those identified under the heading “Risk Factors” in the Company’s Annual Report on Form 10-K for the year ended December 31, 2013 and in any subsequent SEC filings. The forward-looking statements contained in this press release reflect the Company’s current views with respect to future events, and the Company does not undertake and specifically disclaims any obligation to update any forward-looking statements.

Verastem, Inc.

Brian Sullivan, 781-292-4214

bsullivan@verastem.com

Source: Verastem, Inc.


NTHEO Custom Design Jewelry Releases the Second Design of His Latest "Male" Collection: The "Kormos" Ring Oct 24, 2014 06:03AM

Antwerp, Belgium (PRWEB UK) 24 October 2014

This week NTHEO introduces the "kormos" ring.

"Kormos" or "kormoz" is the spiritual devil of the Altaic people. "Kormos" means in Turkic languages "does not see" or "blind." It is an evil and impure spirit. It was also described as a black entity living in the Underworld. This spirit is associated with ancestral spirits and follows a man throughout his lifetime, recording all of his deeds. In Greek it means the torso of a human or a tree trunk. Nikolaos Theodoridis tries to combine and express these two meanings of the word "kormos within this ring. The silver has been carefully sculptured as a tree trunk, filled with deep blue and yellow enamel representing the evil and impure spirit. A commemoration of Nikolaos to the modern man for his deeds in present life and his destiny. The price for the ring is 199€, and it is for sale exclusively at ntheo.net.

For this collection, Nikolaos was inspired by men of different origins who lived in his hometown Thessaloniki in the 1900s, when different cultures and customs made Thessaloniki a cosmopolitan city.

The rings are handmade out of sterling silver and accompanied with exotic woods. Each is individually filled with colorful enamels, semi precious stones, and fine filigree silver work. Each ring can be customized to the wishes of each customer, his style, and budget.

For the next eleven weeks, Theodoridis will introduce each week a new design of this jewelry collection called "Male."

Nikolaos Theodoridis designs, creates, restores, repairs and sets unique jewelry for unique individuals and businesses who are looking for something different then the ordinary jewelry.

You can see his creations at ntheo.net or contact him at info(at)ntheo(dot)net, info(at)ntheo(dot)be, or even call him on +32473304496.

Expertise
Restoration of antique jewelry and silverware basic techniques, sawing, filing, piercing, soldering, etc. • Diamond and gems setting (pave, cluster, channel, gypsy, etc.) • Manual coloring and working of titanium • Coloring of precious metals • Special surface techniques • Granulation and filigree • Enamel cold and warm • Silversmith • Lost wax casting and vacuum • Goldsmith • Rubber mold making • Reparation techniques • Research and development of jewelry products • Knowledge of Rhino 3D software nurbs modelling (cad-cam) • Cost calculation of production • Gem recognition • Platinum work experience

Memberships
Diamond & Jewelry Who's Who, International Jewelry and Accessory Designers, Jewelry & Jewelers, Jewelry & Fashion accessory, benchpeg Jewelry Designer, Jewelry Designers and Jewelry Metal smiths, Luxury Jewelry Professionals and High Jewelry Designers, Silversmiths, Goldsmiths & Jewelers, Women's Jewelry Association

Education
LBC, Antwerp, coarse French. 2006 -2010 Pyz studio, coarse 2005, Antwerp, rhino 4.0, 3-D modelling en rendering software. Technical Higher Education, Antwerp coarse in diamond and gems setting, 2001-2002. INON training center, Antwerp, coarse Windows Word, Excel, 2000. LBC, Antwerp, coarse Italian for beginners 1998-1999. Royal Academy of Fine arts, Antwerp, Masters Degree in Restoration and conservation of metalwork 1991-1994. Royal Academy of Fine arts, Antwerp, bachelor's degree Jewelry design and Master model making 1987-1991. RIKSO, Art school, Antwerp, 7th year, 1986-1987. Allegan High school, Allegan Michigan, US, Exchange program for students, 1984-1985. 4th Lyceum, Thessaloniki, Greece, High school Studies 1977-1983. Languages Greek mother language, English spoken and written, Netherlands spoken and written, Italian basic knowledge, French written and spoken

Read the full story at http://www.prweb.com/releases/2014/10/prweb12272403.htm


Halloween Festivities Draw Family Home Buyers Oct 24, 2014 06:02AM

Palm Springs, CA (PRWEB) October 24, 2014

Brad Schmett, Broker Associate with Luxury Homes by Keller Williams today announced that several scheduled high profile events and activities centered on Halloween and the Dia de los Muertos holidays will prove a big attraction for families looking for spacious family homes in the Palm Springs area.

The Halloween Night Haunted Carriage Ride set for select weekend evenings between now and November 1, 2014 will feature the Headless Horseman with plenty of spooky photo ops along with the Mad Hatter carriage driver sharing ghost stories during the 30 minute tour route through Palm Springs. Not to be left out, the Palm Desert Library will feature their Halloween party on Wednesday, October 27 and on the same day the Fifth Annual Pumpkin Decorating Contest will thrill adults and kids alike at Forest Lawn in Cathedral City.

Schmett observed that, "Even though Halloween is traditionally about children and trick-or-treating, it is also an extremely popular adult holiday as well. My team and I always experience a big upsurge in family home shopping during the holidays, beginning with Halloween. Fortunately, we have some very beautiful and spacious family homes in our inventory that can accommodate extended families of any size. We are all excited to meet new friends and neighbors that are heading in to celebrate all of the wonderful holidays of autumn. This a very special time of year."

The Annual Halloween Carnival in La Quinta will be held October 29 along with the Harvest Fun Fair in Indian Wells and the Palm Desert Haunted House. On Friday, October 31, the Howl-O-Ween Harvest Happening at the Living Desert will be one of the most highly attended events of the season along with the annual Palm Desert Golf Cart Parade.

For more information on Halloween Events in Palm Springs, visit http://palmsprings.com/calendar_of_events.

To find out more about investing in Palm Springs, CA real estate, visit palmspringsrealestateinfo.com.

About Luxury Homes by Keller Williams: Luxury Homes by Keller Williams – Palm Springs, is an exclusive, elite and sophisticated group of real estate consultants raising the bar for service in the Palm Springs area residential real estate market.

Read the full story at http://www.prweb.com/releases/Halloween/Palm-Springs/prweb12274969.htm


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