U.S. Environmental Protection Agency (EPA) Awards Vala Sciences a Second ToxCast Contract Jul 30, 2014 03:05AM

San Diego, CA (PRWEB) July 30, 2014

Vala Sciences was recently awarded a second contract from the U.S. Environmental Protection Agency (EPA). This new contract was awarded for the company's expertise in developmental toxicity models, including tests designed to assess the effect of chemical compounds on neuron formation and the formation of connections between neurons (synapses), which are critical for brain function. Inhibition of neurodifferentiation and synapse formation by environmental pollutants likely contributes to a variety of disorders including mental retardation, autism, Alzheimer's and Parkinson's Disease. Vala's assays enable compounds to be tested on human neurons without using animals.

The contract awards up to $10,637,000 to study the morphological and physiological defects that take place during prenatal or postnatal life, resulting from environmental toxins. As part of the ToxCast program, this funding will be used to further our collective knowledge and gain additional experience towards understanding differing toxicity levels and their effects on the developing human system. The project was awarded based on the team's biology expertise and their use of novel high content screening capabilities.

Vala Sciences is one of 4 companies to be awarded contracts to participate in the most recent phase of ToxCast research. Overall, Vala Sciences will test the toxicity levels for up to 10,000 chemical compounds from the EPA. For their work on the ToxCast program, so far, Vala received an "Exceptional" rating from the EPA for all aspects of performance.

The new project targets additional information on how a compound's toxicity profile can relate to the morphological and physiological defects that take place during prenatal and postnatal development. Special areas of interest are as follows: neural crest formation and migration (forming the skeleton and cartilage of the body), palatogenesis (the roof of the mouth), neurodevelopment and urogenital morphogenesis (nervous system and urinary/genitalia changes), which include both male and female reproductive organs, among some others.

"Historically, determining toxicity profiles would require extensive animal testing", stated Dr. Patrick McDonough, Vala's Vice President of Biology, "but as the EPA strives to reduce the number of animals tested, Vala Sciences is helping to lead the charge by shifting towards more technology-based assessments which utilize cell, organ or organism culture systems with complex and diverse biological capacities, in order to measure chemical effects on critical pathways, processes and phenotypes relevant to human and ecological toxicity".

About Vala Sciences

Vala Sciences is a specialty biotechnology company bringing to bear the combination of Biology, Engineering and Computer Science to deliver automated, high throughput toxicity assessment of drug candidates as an integral part of early stage drug discovery.

Vala's proprietary pro arrhythmia kinetic imaging assay is a rapid, low cost, multi-channel screen that can significantly reduce the cost, and speed the process, of cardiac safety assessment, limitations of which cause almost 35% of all drug failures and market withdrawals that cost the industry about $2.5 B per year.

Further Information
Vala Sciences
6370 Nancy Ridge Dr. #106
San Diego, CA 92121
1-888-742-VALA
1-858-461-6868

Contact for Media Inquiries:
Martin Stuart
VP Commercial Operations
mstuart(at)valasciences(dot)com
http://www.valasciences.com

Read the full story at http://www.prweb.com/releases/2014/07/prweb12049135.htm


Philadelphia Car Accident Lawyer at Flager & Associates Comments on Report about Dangerous Intersections Jul 30, 2014 03:05AM

(PRWEB) July 30, 2014

Philadelphia car accident attorney Randall Flager of Flager & Associates today said a recent news article identifying the top 10 intersections for car crashes should serve as a warning to all drivers to be extra cautious when traveling through these areas.

Flager today commented on a July 10 article in NBC10.com that ranked the city's most notorious intersections. According to the story, seven out of 10 of the most dangerous intersections in the city can be found along Roosevelt Boulevard. The most dangerous intersection, however, is in the Fishtown neighborhood at Delaware Avenue & Frankford Avenue, which had 29 accidents in the first half of 2014, according to the article. That location is just outside the entrance to SugarHouse Casino, according to the story.

"Any intersection can be dangerous for drivers and pedestrians," Flager said. "Collisions tend to occur at intersections more frequently than on sections of the roadway where there are no stop signs or traffic lights. Intersection collisions often happen because a driver runs a red light or fails to yield the right of way to another motorist, pedestrian or bicyclist. That's why it's extremely important for drivers to use caution at any intersection, but be especially careful when driving through these intersections that are deemed 'the most dangerous.'"

According to NBC10.com, the top 10 list is based on data from the Philadelphia Police Department. The following is the full list of the most dangerous intersections in Philadelphia with the number of vehicular crashes between Jan. 1, 2014, and June 15, 2014, according to NBC10.com:

1. Delaware Avenue & Frankford Avenue: 29
2. North 9th Street & Roosevelt Boulevard: 23
3. Roosevelt Boulevard & Fox Street: 22
4. Grant Avenue & Roosevelt Boulevard: 22
5. Lincoln Drive & Gypsy Lane: 21
6. Harbison Avenue & Roosevelt Boulevard: 21
7. 26th Street & Penrose Avenue: 20
8. Roosevelt Boulevard & Ridge Avenue: 19
9. Roosevelt Boulevard & Adams Avenue: 19
10. Red Lion Road & Roosevelt Boulevard: 18

Flager said the types of intersection accident injury claims his law firm has handled cover a wide range, including rear-end collisions, head-on crashes, T-bone or broadside accidents and more. He said drivers who are careless or reckless in and around intersections pose a serious danger to others on the road.

"Many of these accidents involve a negligent driver who is speeding, drunk driving or distracted by a cellphone or something else," Flager said. "People injured in intersection accidents often face long-term medical bills. They're often forced to miss work for an extended period of time. The financial burdens can be overwhelming. Our goal is to help people through these difficult times. We work hard to get them the compensation they need to move on with their lives."

The NBC10.com article cited is "Top Philly Intersections for Car Crashes."

About Flager & Associates

With offices in Trevose, New Hope, Philadelphia, and New Jersey, Flager & Associates serves the legal needs of personal injury victims throughout the five-county area. Working tirelessly to protect the rights of injury victims involved in car and truck accidents, motorcycle accidents, slip and fall accidents, dog attacks, and many other types of personal injury cases, Flager & Associates has a well-earned reputation as a Philadelphia law firm that fights diligently to earn clients the compensation they deserve. An AV-rated Philadelphia personal injury attorney, Randall Flager is a member of the Million Dollar Advocates Forum, reserved for a small percentage of trial attorneys who have obtained settlements or verdicts totaling over $1 million for their clients.

If you've been injured in a car accident, discuss your legal options with a Philadelphia personal injury attorney. Call Flager & Associates at 215-953-5200 for a free case evaluation.

Flager & Associates main office is located at:

1210 Northbrook Dr
Feasterville-Trevose, PA 19053
http://www.flagerlaw.com/

Read the full story at http://www.prweb.com/releases/intersection-accident/lawyers-pa/prweb12051185.htm


Stonegate Financial Group Discusses the First Half of 2014 in an Economic Update Jul 30, 2014 03:05AM

Scottsdale, Arizona (PRWEB) July 30, 2014

Despite the fears that many investors had about the state of the United States economy in the first half of 2014, many gains have been seen in the market. Stonegate Financial Group and Jameson Van Houten share that the country's housing industry saw huge improvement. In fact, existing-home sales went up nearly five percent, the strongest gain this market has seen in three years while new-home sales jumped up a whopping 18.6 percent in May for the largest gain this market has had in more than 20 years. It is truly a buyer's market.

The question now is whether these gains will hold through the end of the year. Stonegate Financial Group and Jameson Van Houten hope so, but know that there is no way of telling for sure.

One positive development that has contributed to driving recent market gains is that price-to-earnings ratios have risen over the past two years, increasing investor confidence. Investors need to be aware, though, that there are still bears and that many professionals, including Nobel Prize-winning professor Robert Shiller, are telling investors simply to be cautious, but not to sell everything off.

Stonegate Financial Group and Jameson Van Houten do note however that financial markets around the world are seeing a boost due to the activities going on in China. Because China upped its manufacturing activity, it is believed that the country will continue to need and consume an enormous amount of raw materials. Though some were worried about slowing economic growth in China, the government set many measures into place in order to make investors feel more confident including business tax breaks, highway spending, credit easing and several other measures.

Over in Europe, Germany and the United Kingdom continue to be the driving force behind the European Economic Expansion, but other countries are starting to contribute more, suggesting that there may be a more cyclical upturn in their market.

Stonegate Financial Group and Jameson Van Houten are aware that the world of investments can become very confusing, very quickly. For more information about any of the topics discusses, visit Stonegate Financial Group, based out of Scottsdale, Arizona, at http://stonegatefg.com or call (602) 953-8450.

Read the full story at http://www.prweb.com/releases/StonegateFinacialGroup/JamesonVanHouten/prweb12050116.htm


Wilmington, NC Car Accident Attorney Richard Flexner Comments on North Carolina "Move Over" Law and Driver Awareness Jul 30, 2014 03:05AM

Wilmington, NC (PRWEB) July 30, 2014

A WRAL-TV news report states that most drivers don't know about the state's "Move Over" law that protects roadside workers, a finding that troubles North Carolina car accident lawyer Richard Flexner of Richard Flexner Law Offices.

"This is very disturbing, because people's lives are at risk," Flexner said. "But fortunately the state will be ramping up awareness of the law. We hope this campaign will lead to a reduction in accident fatalities."

Flexner based his comments on an article published by WRAL-TV on June 27, "NC DOT promoting 'Move Over' law." Flexner said that efforts by the North Carolina Department of Transportation (DOT) to increase awareness of the law is key to protecting the safety of North Carolina emergency personnel stopped at the side of the road.

"North Carolina's 'Move Over' law has been effect since 2002, yet Department of Transportation data suggests more than 1,400 drivers were cited for violations of this important law in 2013 alone," Flexner said. "Each of these violations represents a scenario in which a police officer, paramedic, firefighter, or tow truck driver was put in immediate danger. 'Move Over' laws exist to protect these important emergency personnel from harm. Any failure to comply with the law could result in a catastrophic accident."

According to WRAL-TV, the state's "Move Over" law requires drivers to switch traffic lanes or slow their vehicle down when approaching emergency and public service vehicles. The law was expanded in 2012 to include utility vehicles and road maintenance operations, the article states.

WRAL-TV said the Department of Transportation reported more than 1,400 citations of the "Move Over" law in 2013 alone. In response, WRAL-TV reported the DOT to have launched a safety campaign to remind drivers about the law, including radio advertisements, billboards and reminders on electronic message boards.

"Not knowing the law is no excuse if you are a driver who causes an accident," Flexner said. "People who don't move over and injure or kill another person must be held accountable. While these drivers did not mean to hurt anyone, they nevertheless have acted negligently."

Flexner said an attorney can help injured victims and families who lost loved ones pursue compensation to help them move on with their lives.

About the Law Offices of Richard Flexner

For over 35 years, attorney Richard Flexner has fought diligently to protect the rights of personal injury victims and families who have lost loved ones in Wilmington and across North Carolina. In addition to handling cases involving drunk driving and impaired accidents and other matters involving personal injury and wrongful death, Flexner represents North Carolinians who need assistance with workers' compensation claims. Flexner serves New Hanover County, Brunswick County, Pender County and all of North Carolina. He is a member of the North Carolina Advocates for Justice.

If you were injured, or a loved one was injured or killed in a car accident, call 800-FLEXNER today for a free case consultation.

The Law Offices of Richard Flexner is located at:
3805 Oleander Drive
Wilmington, NC 28403
http://www.getflexner.com

Read the full story at http://www.prweb.com/releases/roadside-accident/attorney-nc/prweb12051273.htm


Advantest's Global Deployment of New MPT3000 Testers for Solid-State Drives Commences With Multiple Orders Jul 30, 2014 03:05AM

TOKYO, JAPAN -- (Marketwired) -- 07/30/14 -- Leading semiconductor test equipment supplier Advantest Corporation (TSE: 6857) (NYSE: ATE) has received multiple MPT3000 system orders from prominent manufacturers of solid-state drives (SSDs). The new testers, just introduced in June, have been successfully installed in the customers' facilities and are being used in testing next-generation SSD devices that are soon to become commercially available.

The multi-protocol MPT3000, being used initially for testing PCIe Gen 3 NVMe enterprise SSDs, was chosen for its performance and easy-to-use software, fast bring-up from installation to results and Advantest's excellent global support. The systems are now in use to accelerate SSD product development and the ramp up to production.

To provide an efficient test solution for the SSD market, the MPT3000 combines Advantest's expertise in high-speed system-on-chip (SoC) testing with state-of-the-art electronics architecture, including proprietary hardware acceleration and performance up to 12 Gbps. The system's multi-protocol capability and high parallelism enable full performance testing of a variety of SSD form factors including half- and full-height PC cards, 2.5-inch drives, M.2 and devices with customized form factors.

Advantest will be showcasing the new MPT3000 system in its booth, #614-615, at the Flash Memory Summit, August 5-7 in Santa Clara, California.

About Advantest Corporation A world-class technology company, Advantest is the leading producer of automatic test equipment (ATE) for the semiconductor industry and a premier manufacturer of measuring instruments used in the design and production of electronic instruments and systems. Its leading-edge systems and products are integrated into the most advanced semiconductor production lines in the world. The company also focuses on R&D for emerging markets that benefit from advancements in nanotech and terahertz technologies, and has introduced multi-vision metrology scanning electron microscopes essential to photomask manufacturing, as well as a groundbreaking 3D imaging and analysis tools. Founded in Tokyo in 1954, Advantest established its first subsidiary in 1982, in the USA, and now has subsidiaries worldwide. More information is available at www.advantest.com.

Advantest Corporation
3061 Zanker Road
San Jose, CA 95134, USA
Judy Davies
Email Contact

Source: Advantest


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