Metabasis Therapeutics (MBRX) Announces Research Collaboration Agreement with Roche

August 7, 2008 4:18 PM EDT

Metabasis Therapeutics, Inc. (Nasdaq: MBRX) announced today that it has entered into a two-year research collaboration agreement with Roche to apply Metabasis’ HepDirect liver-targeting technology to Roche’s proprietary lead nucleosides in order to develop new treatments for hepatitis C virus (HCV).

Under the terms of the agreement, Roche will provide a $10 million upfront payment. In the event a development candidate is identified, Roche will assume development responsibility, and Metabasis will be eligible to receive up to $193 million in additional payments upon achievement of predetermined preclinical and clinical development events, as well as regulatory and commercialization events for each product. For any marketed products that result from the collaboration, Roche will retain full commercial rights and pay Metabasis a royalty on net sales.


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