SuperGen Inc. (SUPG) MP-470 Demonstrates Clinical Benefit in Lung Cancer Patients
SuperGen Inc., (NASDAQ: SUPG) announced that Phase Ib data for MP-470, its multi-targeted, tyrosine kinase inhibitor and RAD51 suppressor, demonstrated an overall clinical benefit rate of 54 percent when the drug is given in combination with standard of care (SOC) anti-cancer therapies in patients with non-small cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). The data was presented at a poster session on Saturday at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO) in Lugano, Switzerland.
The Phase Ib dose escalation study enrolled thirteen poor prognosis patients: nine with NSCLC and four with SCLC as of August 31, 2008. Of eleven evaluable patients, only one showed progressive disease, five showed stable disease, and five showed partial response. MP-470 did not alter the pharmacokinetics of SOC agents.
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