Rosetta Genomics (ROSG) Receives Two Additional Patent Allowances Related to microRNA Platform Tech

October 3, 2016 8:05 AM EDT
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Rosetta Genomics Ltd. (Nasdaqq: ROSG) announced that the Company has added two new patent allowances to its intellectual property portfolio for its microRNA platform technology. With these new allowances, Rosetta Genomics has 64 granted or allowed patents and 33 patents pending.

Rosetta Genomics has received a Notice of Allowance from the U.S. Patent and Trademark Office (USPTO) for U.S. Patent Application No. 12/999,201, entitled, “Compositions and Methods for Prognosis of Ovarian Cancer.” The allowed patent claims a method of predicting progression of platinum-resistant stage III ovarian cancer in response to platinum-based chemotherapy, based on the expression of hsa-miR-27a in an ovarian tumor sample.

“Almost 20% of women who receive standard platinum- and paclitaxel-based treatment for ovarian cancer are found to be resistant to antineoplastic chemotherapy. The majority of women with advanced ovarian cancer will ultimately relapse and develop drug-resistant disease, making a marker for platinum-resistant cancers particularly useful for the determination of second-line chemotherapeutic options,” noted Kenneth A. Berlin, President and Chief Executive Officer of Rosetta Genomics. “This U.S. ovarian cancer prognostic patent complements a recently allowed U.S. patent covering a method of treatment for ovarian cancer through the administration of an inhibitor of miR-27a. Together these patents may be of great value in the development of new prognostic and treatment options for platinum-resistant ovarian cancer patients. Our goal is to monetize these U.S. patents and the related technology through a potential partnership.”

The company also received a Notice of Allowance from the Korean Intellectual Property Office (KIPO) for Korean Patent Application No. 2010-7007495, entitled, “Diagnosis and Prognosis of Specific Cancers.” The allowed patent claims a method for diagnosing pleural mesothelioma or distinguishing between pleural mesothelioma and other cancers, using the expression profile of hsa-miR-192, hsa-miR-200c and hsa-miR-193a. Corresponding U.S. Patent 9,133,522 has been granted in the U.S.

“Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs, the most common kind being pleural mesothelioma, where the lining of the lungs and chest wall is affected. Greater than 80% of mesothelioma is caused by exposure to asbestos. This assay expands our robust diagnostic offering in lung cancer diagnostics and prognostics,” added Mr. Berlin.

“The strength and breadth of our microRNA patent portfolio is unparalleled and further demonstrates the robustness, versatility and prolific potential of these platforms,” concluded Mr. Berlin.

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