Great Basin Scientific (GBSN) Receives U.S. Patent Related to PCR Amplification Suppressor

November 29, 2016 7:32 AM EST

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Great Basin Scientific, Inc. (OTC: GBSN) announced that the United States Patent and Trademark Office (USPTO) issued U.S. Patent 9,434,999 for the company’s amplification suppressor. This technology blocks detection of contaminants present in the environment that may result in a false positive result and potential misdiagnosis of a patient.

The high sensitivity of molecular diagnostic testing makes it vulnerable to the influence of common environmental contaminants such as Staphylococcus epidermidis, which is widely found on skin and public surfaces. To provide for higher test specificity, Great Basin has developed this “amplification suppressor” strategy that can eliminate detection of Staphylococcus species or any other bacteria environmental contaminant when testing clinical specimens such as blood specimens, nasal swabs, or bronchial lavages from suspected pneumonia. The amplification suppressor is used in the Company’s Staph ID/R Blood Culture Panel and is being utilized in the SA Nasal Screen Test, slated for clinical trial in the first half of 2017, as well as future tests and panels.

“In the molecular diagnostics community, concern that a positive test result is actually indicating an environmental contaminant—as opposed a life-threatening organism—has long been an industry concern,” said Robert D. Jenison, chief technology officer of Great Basin Scientific. “Great Basin’s amplification suppressor strategy assures clinicians receive accurate, actionable results that will define a clear treatment path for these ill patients, and supports the Company’s commitment to deliver some of the industry’s most accurate and fast molecular tests. We’re pleased to receive this patent to further protect our assets and portfolio of unique technology.”

With this patent grant, Great Basin has seven U.S. patents issued and 12 patents pending.

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