Sonus Networks (SONS) Acquires Taqua in $20M+ Deal; Reaffirms Outlook Sep 26, 2016 05:27PM

Sonus Networks, Inc. (Nasdaq: SONS) announced its acquisition of Taqua, LLC, a leading supplier of IP communications systems, applications and services to mobile and fixed operators, in an all-cash transaction. The acquisition closed on September 26, 2016.

There will be a conference call hosted by Ray Dolan, President and CEO, and Susan Villare, interim CFO, on Tuesday, September 27, 2016, at 8:30 a.m. (ET) to discuss the highlights of this transaction.

Overview of Taqua

XBiotech (XBIT) Enters $50.3M Stock Sales Agreement Sep 26, 2016 05:26PM

XBiotech (NASDAQ: XBIT)disclosed the following in a U.S. SEC filing on Monday:

Item 1.01 Entry into a Material Definitive Agreement.

Common Stock Sales Agreement with H.C. Wainwright

On September 26, 2016, XBiotech Inc. (“we,” “us” or the “Company”) entered into a Common Stock Sales Agreement (the “Sales Agreement”) with H.C. Wainwright & Co. LLC (“H.C. Wainwright”) which establishes an at-the-market equity program pursuant to which we may offer and... (continue reading...)

Trillium Therapeutics (TRIL) Presents Data on TTI-621 in Blocking CD47 'Do Not Eat' Signal Sep 26, 2016 05:23PM

Trillium Therapeutics (NASDAQ: TRIL) presents data on TTI-621 (SIRPαFc) in blocking CD47 "do not eat" signal today. Key points from the presentation (which is embedded below):

  • CD47 binds to SIRPo on the surface of macrophages and delivers a "do not eat" signal to suppress phagocytosis
  • Tumor cells frequently overexpress CD47 and exploit this pathway to evade macrophage-mediated destruction
  • Blocking CD47 using TTI-621, a soluble SIRPαFc decoy receptor fused to a human... (continue reading...)

Infinity Pharma (INFI) Announces presentation of Positive Preclinical Data on IPI-549 Sep 26, 2016 05:17PM

Infinity Pharmaceuticals, Inc. (Nasdaq: INFI) announced initial clinical and new preclinical data for IPI-549, an orally administered immuno-oncology development candidate that selectively inhibits PI3K-gamma. Preliminary Phase 1 results from nine patients with advanced solid tumors show that the safety, pharmacokinetics and pharmacodynamics of IPI-549 monotherapy treatment appear favorable. Additionally, new preclinical data demonstrate that IPI-549 can reverse tumor... (continue reading...)

Pieris Pharma (PIRS) Says It Presented Positive Data for Lead Drug Candidate PRS-343 Sep 26, 2016 05:16PM

Pieris Pharmaceuticals, Inc. (NASDAQ: PIRS) announced that it has today presented new preclinical data demonstrating in vivo efficacy of its lead 4-1BB (CD137)-based bispecific cancer immunotherapeutic drug candidate, PRS-343, at the 2016 CRI-CIMT-AACR International Cancer Immunotherapy Conference - Translating Science into Survival, taking place in New York City.

The in vivo data show that treatment of HER2-positive tumor-bearing animals with PRS-343 provided... (continue reading...)

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