Alnylam Pharma (ALNY) To Provide RNAi Pipeline, Platform, and Tech Update at R&D Day in NY

November 12, 2009 7:30 AM EST

Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) is providing an update on its RNAi pipeline, platform, and technology at its R&D Day being held in New York today. Alnylam scientists and management will be joined by two guest speakers: Professor Allan Glanville, Director of Thoracic Medicine and Medical Director Lung Transplantation, St. Vincent’s Hospital, Sydney, will discuss respiratory syncytial virus (RSV) infection in the lung transplant patient population; and Professor Philip N. Hawkins, National Amyloidosis Centre, Division of Medicine, and University College London Medical School, Royal Free Hospital, will discuss transthyretin (TTR)-mediated amyloidosis (ATTR). Alnylam is developing RNAi therapeutics for the treatment of both RSV infection and ATTR, amongst other pipeline programs.

Alnylam is developing ALN-TTR, a systemically delivered RNAi therapeutic targeting the TTR gene for the treatment of ATTR, including familial amyloidotic cardiomyopathy (FAC) and familial amyloidotic polyneuropathy (FAP). ATTR is caused by mutations in the TTR gene, which is expressed in the liver, that result in the accumulation of toxic deposits of the mutant TTR protein in several tissues, including nerves, heart, and the gastrointestinal tract.


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