Wedbush Reiterates an 'Underperform' on Dendreon (DNDN); New Treatments in Prostate Cancer Could Leave Provenge Behind

June 4, 2012 9:05 AM EDT Send to a Friend
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Price: $3.95 --0%

Rating Summary:
    5 Buy, 15 Hold, 12 Sell

Rating Trend: Down Down

Today's Overall Ratings:
    Up: 0 | Down: 0 | New: 8
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Wedbush reiterates an 'Underperform' on Dendreon (NASDAQ: DNDN) price target of $4.00 (from $5.00).

Analyst, David M. Nierengarten, said, "Positive data from Zytiga’s ‘302 Phase III trial in pre-chemotherapy prostate cancer patients will reduce the available patient population for Dendreon’s Provenge, in our opinion. The full ‘302 dataset for Zytiga at ASCO on Saturday showed Zytiga-treated patients had a statistically significant improvement in progression-free survival (PFS), with a hazard ratio of 0.43 compared to placebo. Overall survival showed a trend (HR of 0.75 in the Zytiga group) that missed statistical significance (but could become significant with final data)."

"We are reducing our sales estimates for Provenge to $336.2M, $385.5M, $441.6M, and $489.9M for 2012-2015...We would caution investors who believe that DNDN could be a takeover target. In our view, an acquirer would be very unlikely to purchase a lowmargin product like Provenge in a rapidly evolving treatment paradigm."

For an analyst ratings summary and ratings history on Dendreon click here. For more ratings news on Dendreon click here.

Shares of Dendreon closed at $6.76 yesterday, with a 52 week range of $6.46-$42.06.


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