Deutsche Bank Takeways from EASL (GILD) (ABBV) (MRK) (IDIX) (ACHN)

April 10, 2014 1:45 PM EDT Send to a Friend
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In a research note Thursday, Deutsche Bank analyst Robyn Karnauskas commented with takeways so far from the EASL conference in London. Company's mentioned in the note include Gilead Sciences (Nasdaq: GILD), AbbVie (ABBV), Merck (NYSE: MRK), Idenix Pharmaceuticals (NASDAQ: IDIX) and Achillion Pharmaceuticals (NASDAQ: ACHN).

"GILD: Not a lot of data so far, everything looks solid. Gilead appears to be dominant regimen. Some chatter about how 5816 (second generation) is going to be the dominant pan-genotypic drug that can treat everyone. This could be 2016 launch.

"Abbvie: saw one study in experienced patients, need to see Tourquise2 (Saturday) to see how this combo reads out in cirrhotic patients. We have not seen pan-genotypic data from them so far (likely at AASLD).

"Merck: Solid GT1 data, 8 weeks doesn’t look as good, one patient relapsed (chatter about this patient- we need to learn more about this patient that had new or mixed infection that was GT2 and 3) and there is concern that at low doses drug combo is not pan genotypic but it looks clean for GT 1,4,5,6. It is fairly well known that this regimen at that low doses of the PI may not be pan genotypic. At 800mg this combo had liver tox. Doesn’t look like they can do 8 weeks.

"IDIX/ACHN: Chatter upon viewing Merck/Abbive data, Merck & Abbvie could need a nuke to really be pan genotypic and have lower duration, this could benefit companies with nukes like Idenix and Achillion," said Karnauskas.



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